CNTF Protein, Mouse, Recombinant

Name: CNTF Protein, Mouse, Recombinant
Brand: TargetMol
SKU: TMPS-00181
Rating: 4.5 (1 reviews)

(Synonyms: Ciliary neurotrophic factor) Copy Product Info

Synonyms: Ciliary neurotrophic factor

Catalog No. TMPS-00181 Copy Product Info

CNTF Protein, Mouse, Recombinant is expressed in E. coli. The accession number is P51642.

Pack Size	Price	USA Stock	Global Stock
5 µg	$129	7-10 days	7-10 days
10 µg	$215	7-10 days	7-10 days
20 µg	$355	7-10 days	7-10 days
50 µg	$697	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it.
Description	CNTF Protein, Mouse, Recombinant is expressed in E. coli. The accession number is P51642.
Species	Mouse
Expression System	E. coli
Tag	Tag Free
Accession Number	P51642
Construction	Ala2-Met198
Protein Purity	> 95% as determined by SDS-PAGE; > 95% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 µm filtered solution in 2 × PBS, pH 7.4, 2 % trehalose.
Reconstitution	It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1 mg/ml.
Synonyms	Ciliary neurotrophic factor
Research Background	Ciliary neurotrophic factor (CNTF) is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. CNTF was initially identified as a trophic factor for embryonic chick ciliary parasympathetic neurons in culture. Furthermore, the protein is also a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. In addition, CNTF is useful for treatment of motor neuron disease and it could reduce food intake without causing hunger or stress. Recombinant murine CNTF containing 198 amino acids and it shares 82 % and 95 % a.a. sequence identity with human and rat CNTF.

Chemical Properties

Molecular Weight

22.5 kDa (Predicted)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at -20°C or -70°C. Upon reconstitution, the product should be stable for up to 1 week at 2-8°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles.