Serpin E2 Protein, Mouse, Recombinant (His)

Name: Serpin E2 Protein, Mouse, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-01083
Rating: 4.5 (1 reviews)

(Synonyms: Spi4, Serpin E2, Serine protease-inhibitor 4, Protease nexin I, Protease nexin 1, PN-1, Pn1, PI-7, Pi7, Peptidase inhibitor 7, Glia-derived nexin, GDN) Copy Product Info

Synonyms: Spi4, Serpin E2, Serine protease-inhibitor 4, Protease nexin I, Protease nexin 1, PN-1, Pn1, PI-7, Pi7, Peptidase inhibitor 7, Glia-derived nexin, GDN

Catalog No. TMPJ-01083 Copy Product Info

Serpin E2 is a member of the Serpin superfamily. It is differentially expressed during neuronal differentiation and is able to transform human embryonic kidney cells into neuronlike cells. Its over-expression in mice leads to progressive neuronal and motor dysfunction in these animals. It is also over-expressed in the majority of pancreatic carcinoma as well as gastric and colorectal cancer samples whereas it is weakly expressed in all normal pancreas and chronic pancreatitis tissue samples. Serpin E2 is a potent inhibitor of thrombin, trypsin, urokinase, plasmin and plasminogen activators. It plays an important role in controlling male fertility because its knockout male mice show a marked impairment in fertility from the onset of sexual maturity and its abnormal expression is found in the semen of men with seminal dysfunction.

Serpin E2 Protein, Mouse, Recombinant (His)

Pack Size	Price	USA Stock	Global Stock
10 µg	$97	35 days	35 days
20 µg	$148	35 days	35 days
50 µg	$272	35 days	35 days
100 µg	$438	35 days	35 days
200 µg	$716	35 days	35 days
500 µg	$1,370	35 days	35 days
1 mg	$1,980	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Serpin E2 is a member of the Serpin superfamily. It is differentially expressed during neuronal differentiation and is able to transform human embryonic kidney cells into neuronlike cells. Its over-expression in mice leads to progressive neuronal and motor dysfunction in these animals. It is also over-expressed in the majority of pancreatic carcinoma as well as gastric and colorectal cancer samples whereas it is weakly expressed in all normal pancreas and chronic pancreatitis tissue samples. Serpin E2 is a potent inhibitor of thrombin, trypsin, urokinase, plasmin and plasminogen activators. It plays an important role in controlling male fertility because its knockout male mice show a marked impairment in fertility from the onset of sexual maturity and its abnormal expression is found in the semen of men with seminal dysfunction.
Species	Mouse
Expression System	HEK293 Cells
Tag	C-10xHis
Accession Number	Q07235
Amino Acid	Ser20-Pro397
Construction	Ser20-Pro397
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM Sodium Acetate, 150 mM NaCl, 5% Trehalose, 5% Mannitol, 0.02% Tween 80, 1 mM EDTA, pH 4.0.
Synonyms	Spi4, Serpin E2, Serine protease-inhibitor 4, Protease nexin I, Protease nexin 1, PN-1, Pn1, PI-7, Pi7, Peptidase inhibitor 7, Glia-derived nexin, GDN
Research Background	Serpin E2 is a member of the Serpin superfamily. It is differentially expressed during neuronal differentiation and is able to transform human embryonic kidney cells into neuronlike cells. Its over-expression in mice leads to progressive neuronal and motor dysfunction in these animals. It is also over-expressed in the majority of pancreatic carcinoma as well as gastric and colorectal cancer samples whereas it is weakly expressed in all normal pancreas and chronic pancreatitis tissue samples. Serpin E2 is a potent inhibitor of thrombin, trypsin, urokinase, plasmin and plasminogen activators. It plays an important role in controlling male fertility because its knockout male mice show a marked impairment in fertility from the onset of sexual maturity and its abnormal expression is found in the semen of men with seminal dysfunction.

Chemical Properties

Molecular Weight

50-55 KDa (reducing condition)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.