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Serpin E2 Protein, Mouse, Recombinant (His)
(Synonyms: Spi4, Serpin E2, Serine protease-inhibitor 4, Protease nexin I, Protease nexin 1, PN-1, Pn1, PI-7, Pi7, Peptidase inhibitor 7, Glia-derived nexin, GDN) Copy Product InfoSynonyms: Spi4, Serpin E2, Serine protease-inhibitor 4, Protease nexin I, Protease nexin 1, PN-1, Pn1, PI-7, Pi7, Peptidase inhibitor 7, Glia-derived nexin, GDN
Catalog No. TMPJ-01083 Copy Product Info
Serpin E2 is a member of the Serpin superfamily. It is differentially expressed during neuronal differentiation and is able to transform human embryonic kidney cells into neuronlike cells. Its over-expression in mice leads to progressive neuronal and motor dysfunction in these animals. It is also over-expressed in the majority of pancreatic carcinoma as well as gastric and colorectal cancer samples whereas it is weakly expressed in all normal pancreas and chronic pancreatitis tissue samples. Serpin E2 is a potent inhibitor of thrombin, trypsin, urokinase, plasmin and plasminogen activators. It plays an important role in controlling male fertility because its knockout male mice show a marked impairment in fertility from the onset of sexual maturity and its abnormal expression is found in the semen of men with seminal dysfunction.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $61 | 35 days | 35 days | |
| 10 μg | $97 | 35 days | 35 days | |
| 20 μg | $148 | 35 days | 35 days | |
| 50 μg | $272 | 35 days | 35 days | |
| 100 μg | $438 | 35 days | 35 days | |
| 200 μg | $716 | 35 days | 35 days | |
| 500 μg | $1,370 | 35 days | 35 days | |
| 1 mg | $1,980 | 35 days | 35 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Serpin E2 is a member of the Serpin superfamily. It is differentially expressed during neuronal differentiation and is able to transform human embryonic kidney cells into neuronlike cells. Its over-expression in mice leads to progressive neuronal and motor dysfunction in these animals. It is also over-expressed in the majority of pancreatic carcinoma as well as gastric and colorectal cancer samples whereas it is weakly expressed in all normal pancreas and chronic pancreatitis tissue samples. Serpin E2 is a potent inhibitor of thrombin, trypsin, urokinase, plasmin and plasminogen activators. It plays an important role in controlling male fertility because its knockout male mice show a marked impairment in fertility from the onset of sexual maturity and its abnormal expression is found in the semen of men with seminal dysfunction. |
| Species | Mouse |
| Expression System | HEK293 Cells |
| Tag | C-10xHis |
| Accession Number | Q07235 |
| Amino Acid | Ser20-Pro397 |
| Construction | Ser20-Pro397 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20 mM Sodium Acetate, 150 mM NaCl, 5% Trehalose, 5% Mannitol, 0.02% Tween 80, 1 mM EDTA, pH 4.0. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Proteins are shipped with blue ice. |
| Synonyms | Spi4, Serpin E2, Serine protease-inhibitor 4, Protease nexin I, Protease nexin 1, PN-1, Pn1, PI-7, Pi7, Peptidase inhibitor 7, Glia-derived nexin, GDN |
| Research Background |
| Molecular Weight | 50-55 KDa (reducing condition) |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Serpin E2 Protein, Mouse, Recombinant (His) chemical structure | Serpin E2 Protein, Mouse, Recombinant (His) molecular weight
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