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Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642)
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Catalog No. TMAC-03174
Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642) is a Rabbit antibody targeting PGC-1 alpha/PGC-1 beta. Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642) can be used in WB.
Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642)
Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642)
😃Good
Catalog No. TMAC-03174
Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642) is a Rabbit antibody targeting PGC-1 alpha/PGC-1 beta. Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642) can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $496 | 7-10 days |
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| Description | Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642) is a Rabbit antibody targeting PGC-1 alpha/PGC-1 beta. Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642) can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:1000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Transcription factors exert their effects by associating with co-activator or corepressor proteins. The co-activator complexes are thought to be constitutively active, requiring only proper positioning in the genome to initiate transcription. Co-activators include the steroid receptor coactivator (SRC) and CREB binding protein (CBP) families that contain histone acetyltransferase (HAT) activity, which modifies chromatin structure. PPARgamma co-activator-1 (PGC-1) is a transcriptional cofactor of nuclear respiratory factor-1 (NRF-1), PPARbeta, PPARalpha and other nuclear receptors that is induced by exposure to cold temperatures and is involved in regulating thermogenic gene expression, protein uncoupling, and mitochondrial biogenesis. PGC-1 has a low inherent transcriptional activity when it is not bound to a transcription factor. Docking of PGC-1 to PPARgamma stimulates an apparent conformational change that then enables PGC-1 to bind to and assemble into complexes, which include the additional cofactors SRC-1 and CBP/p300, and results in a large increase in transcriptional activity. |
| Conjucates | Unconjugated |
| Immunogen | 49410 |
| Antigen Species | Recombinant Protein |
| Uniprot ID |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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