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Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642)
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Catalog No. TMAC-03174
Alias PRGC2, PRGC1, PPARGC-1-beta, Ppargc1b, PPARGC1A, PPARGC1, PPARGC 1 alpha, PPAR-gamma coactivator 1-beta, PPAR-gamma coactivator 1-alpha, PPAR gamma coactivator-1beta, PPAR gamma coactivator variant form, PPAR gamma coactivator 1 alpha 3 ligand effect modulator 6, PPAR gamma coactivator 1 alpha, PPAR gamma coactivator 1, PGC1β, PGC1α, PGC1v, PGC-1-related estrogen receptor alpha coactivator, PGC-1-beta, PGC-1-alpha, PGC1A, PGC-1(beta), PGC1(alpha), PGC1 β, PGC1 α, PGC1, PGC 1v, PGC 1(alpha), peroxisome proliferator-activated receptor gamma coactivator 1 beta, Peroxisome proliferator activated receptor gamma coactivator 1 alpha, Peroxisome proliferative activated receptor, gamma, coactivator 1 alpha, Peroxisome proliferative activated receptor, gamma, coactivator 1, PERC, Ligand effect modulator 6, LEM6
Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642) is a Rabbit antibody targeting PGC-1 alpha/PGC-1 beta. Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642) can be used in WB.
Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642)
Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642)
😃Good
Catalog No. TMAC-03174Alias PRGC2, PRGC1, PPARGC-1-beta, Ppargc1b, PPARGC1A, PPARGC1, PPARGC 1 alpha, PPAR-gamma coactivator 1-beta, PPAR-gamma coactivator 1-alpha, PPAR gamma coactivator-1beta, PPAR gamma coactivator variant form, PPAR gamma coactivator 1 alpha 3 ligand effect modulator 6, PPAR gamma coactivator 1 alpha, PPAR gamma coactivator 1, PGC1β, PGC1α, PGC1v, PGC-1-related estrogen receptor alpha coactivator, PGC-1-beta, PGC-1-alpha, PGC1A, PGC-1(beta), PGC1(alpha), PGC1 β, PGC1 α, PGC1, PGC 1v, PGC 1(alpha), peroxisome proliferator-activated receptor gamma coactivator 1 beta, Peroxisome proliferator activated receptor gamma coactivator 1 alpha, Peroxisome proliferative activated receptor, gamma, coactivator 1 alpha, Peroxisome proliferative activated receptor, gamma, coactivator 1, PERC, Ligand effect modulator 6, LEM6
Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642) is a Rabbit antibody targeting PGC-1 alpha/PGC-1 beta. Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642) can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $496 | 7-10 days |
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| Description | Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642) is a Rabbit antibody targeting PGC-1 alpha/PGC-1 beta. Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642) can be used in WB. |
| Alias | PRGC2, PRGC1, PPARGC-1-beta, Ppargc1b, PPARGC1A, PPARGC1, PPARGC 1 alpha, PPAR-gamma coactivator 1-beta, PPAR-gamma coactivator 1-alpha, PPAR gamma coactivator-1beta, PPAR gamma coactivator variant form, PPAR gamma coactivator 1 alpha 3 ligand effect modulator 6, PPAR gamma coactivator 1 alpha, PPAR gamma coactivator 1, PGC1β, PGC1α, PGC1v, PGC-1-related estrogen receptor alpha coactivator, PGC-1-beta, PGC-1-alpha, PGC1A, PGC-1(beta), PGC1(alpha), PGC1 β, PGC1 α, PGC1, PGC 1v, PGC 1(alpha), peroxisome proliferator-activated receptor gamma coactivator 1 beta, Peroxisome proliferator activated receptor gamma coactivator 1 alpha, Peroxisome proliferative activated receptor, gamma, coactivator 1 alpha, Peroxisome proliferative activated receptor, gamma, coactivator 1, PERC, Ligand effect modulator 6, LEM6 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of PGC1 alpha+beta on different lysates using anti-PGC1 alpha+beta antibody at 1/1,000 dilution. Positive control: Lane 1: Mouse brain, Lane 2: Mouse heart, Lane 3: Mouse kidney. |
| Application | |
| Recommended Dose | WB: 1:1000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Transcription factors exert their effects by associating with co-activator or corepressor proteins. The co-activator complexes are thought to be constitutively active, requiring only proper positioning in the genome to initiate transcription. Co-activators include the steroid receptor coactivator (SRC) and CREB binding protein (CBP) families that contain histone acetyltransferase (HAT) activity, which modifies chromatin structure. PPARgamma co-activator-1 (PGC-1) is a transcriptional cofactor of nuclear respiratory factor-1 (NRF-1), PPARbeta, PPARalpha and other nuclear receptors that is induced by exposure to cold temperatures and is involved in regulating thermogenic gene expression, protein uncoupling, and mitochondrial biogenesis. PGC-1 has a low inherent transcriptional activity when it is not bound to a transcription factor. Docking of PGC-1 to PPARgamma stimulates an apparent conformational change that then enables PGC-1 to bind to and assemble into complexes, which include the additional cofactors SRC-1 and CBP/p300, and results in a large increase in transcriptional activity. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 113 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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