Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642)

😃Good
Catalog No. TMAC-03174

Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642) is a Rabbit antibody targeting PGC-1 alpha/PGC-1 beta. Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642) can be used in WB.

Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642)

Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642)

😃Good
Catalog No. TMAC-03174
Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642) is a Rabbit antibody targeting PGC-1 alpha/PGC-1 beta. Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642) can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4967-10 days
Add to Cart
Add to Quotation
Bulk & Custom
Questions
View More
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642) is a Rabbit antibody targeting PGC-1 alpha/PGC-1 beta. Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642) can be used in WB.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundTranscription factors exert their effects by associating with co-activator or corepressor proteins. The co-activator complexes are thought to be constitutively active, requiring only proper positioning in the genome to initiate transcription. Co-activators include the steroid receptor coactivator (SRC) and CREB binding protein (CBP) families that contain histone acetyltransferase (HAT) activity, which modifies chromatin structure. PPARgamma co-activator-1 (PGC-1) is a transcriptional cofactor of nuclear respiratory factor-1 (NRF-1), PPARbeta, PPARalpha and other nuclear receptors that is induced by exposure to cold temperatures and is involved in regulating thermogenic gene expression, protein uncoupling, and mitochondrial biogenesis. PGC-1 has a low inherent transcriptional activity when it is not bound to a transcription factor. Docking of PGC-1 to PPARgamma stimulates an apparent conformational change that then enables PGC-1 to bind to and assemble into complexes, which include the additional cofactors SRC-1 and CBP/p300, and results in a large increase in transcriptional activity.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
49410
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642) | purchase Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642) | Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642) cost | order Anti-PGC-1 alpha/PGC-1 beta Antibody (4J642)