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4-tert-Octylphenol

🥰Excellent
Catalog No. T64353Cas No. 140-66-9

4-tert-Octylphenol, an endocrine-disrupting chemical with estrogenic properties, notably induces apoptosis in offspring mouse brain neuronal progenitor cells. This compound decreases levels of bromodeoxyuridine (BrdU), mitotic marker Ki67, and phospho-histone H3 (p-Histone-H3), thereby diminishing the proliferation of neuronal progenitors. Consequently, 4-tert-Octylphenol adversely affects brain development and behavior in mice.

4-tert-Octylphenol

4-tert-Octylphenol

🥰Excellent
Purity: 99.77%
Catalog No. T64353Cas No. 140-66-9
4-tert-Octylphenol, an endocrine-disrupting chemical with estrogenic properties, notably induces apoptosis in offspring mouse brain neuronal progenitor cells. This compound decreases levels of bromodeoxyuridine (BrdU), mitotic marker Ki67, and phospho-histone H3 (p-Histone-H3), thereby diminishing the proliferation of neuronal progenitors. Consequently, 4-tert-Octylphenol adversely affects brain development and behavior in mice.
Pack SizePriceAvailabilityQuantity
5 g$29In Stock
1 mL x 10 mM (in DMSO)$29In Stock
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Purity:99.77%
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Product Introduction

Bioactivity
Description
4-tert-Octylphenol, an endocrine-disrupting chemical with estrogenic properties, notably induces apoptosis in offspring mouse brain neuronal progenitor cells. This compound decreases levels of bromodeoxyuridine (BrdU), mitotic marker Ki67, and phospho-histone H3 (p-Histone-H3), thereby diminishing the proliferation of neuronal progenitors. Consequently, 4-tert-Octylphenol adversely affects brain development and behavior in mice.
Chemical Properties
Molecular Weight206.32
FormulaC14H22O
Cas No.140-66-9
SmilesCC(C)(C)CC(C)(C)C1=CC=C(O)C=C1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 45 mg/mL (218.11 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.8468 mL24.2342 mL48.4684 mL242.3420 mL
5 mM0.9694 mL4.8468 mL9.6937 mL48.4684 mL
10 mM0.4847 mL2.4234 mL4.8468 mL24.2342 mL
20 mM0.2423 mL1.2117 mL2.4234 mL12.1171 mL
50 mM0.0969 mL0.4847 mL0.9694 mL4.8468 mL
100 mM0.0485 mL0.2423 mL0.4847 mL2.4234 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

Human Endogenous MetaboliteEndogenousMetaboliteEndogenous Metabolite4-tert-Octylphenol4tertOctylphenol
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