Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-Insulin Receptor Antibody (5X84)

😃Good
Catalog No. TMAC-02169

Anti-Insulin Receptor Antibody (5X84) is a Rabbit antibody targeting Insulin Receptor. Anti-Insulin Receptor Antibody (5X84) can be used in WB,ICC/IF.

Anti-Insulin Receptor Antibody (5X84)

Anti-Insulin Receptor Antibody (5X84)

😃Good
Catalog No. TMAC-02169
Anti-Insulin Receptor Antibody (5X84) is a Rabbit antibody targeting Insulin Receptor. Anti-Insulin Receptor Antibody (5X84) can be used in WB,ICC/IF.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4987-10 days
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View More

Product Introduction

Bioactivity
Description
Anti-Insulin Receptor Antibody (5X84) is a Rabbit antibody targeting Insulin Receptor. Anti-Insulin Receptor Antibody (5X84) can be used in WB,ICC/IF.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000-2000; ICC/IF: 1:100-500
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe insulin receptor (IR) is a heterodimeric protein complex that has an intracellular β subunit and an extracellular α subunit, which is disulfide- linked to a transmembrane segment. The insulin ligand binds to the IR and initiates molecular signaling pathways that promote glucose uptake in cells and glycogen synthesis. Insulin binding to IR induces phosphorylation of intracellular tyrosine kinase domains and recruitment of multiple SH2 and SH3 domain-containing intracellular proteins that serve as signaling intermediates for pleiotropic effects of insulin. The human insulin receptor gene maps to chromosome 19p13.3-p13.2 and encodes a 1382 amino acid protein that cleaves to form α and β subunits. Type 1 diabetes is an auto-immune condition of the endocrine pancreas that results in destruction of insulin secreting cells and a progressive loss in insulin-sensitive glucose uptake by cells. Type 2 diabetes is a condition where cells become resistant to insulin action.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthesized peptide: within human Insulin receptor aa 930-970
Antigen Species
human
Gene ID
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 156 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Anti-Insulin Receptor Antibody (5X84) | purchase Anti-Insulin Receptor Antibody (5X84) | Anti-Insulin Receptor Antibody (5X84) cost | order Anti-Insulin Receptor Antibody (5X84) | Anti-Insulin Receptor Antibody (5X84) molecular weight