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Anti-Insulin Receptor Antibody (5X84)
(Synonyms: Insulin Receptor, HHF5, CD220) Copy Product Info
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Synonyms: Insulin Receptor, HHF5, CD220
Catalog No. TMAC-02169 Copy Product Info
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Anti-Insulin Receptor Antibody (5X84) is a Rabbit antibody targeting Insulin Receptor. Anti-Insulin Receptor Antibody (5X84) can be used in ICC/IF,WB.
Anti-Insulin Receptor Antibody
(5X84)
(5X84)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $298 | 7-10 days | 7-10 days | |
| 100 μL | $498 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Insulin Receptor Antibody (5X84) is a Rabbit antibody targeting Insulin Receptor. Anti-Insulin Receptor Antibody (5X84) can be used in ICC/IF,WB. |
| Synonyms | Insulin Receptor, HHF5, CD220 |
| Ig Type | IgG |
| Clone | 5X84 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:1000-2000; ICC/IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The insulin receptor (IR) is a heterodimeric protein complex that has an intracellular β subunit and an extracellular α subunit, which is disulfide- linked to a transmembrane segment. The insulin ligand binds to the IR and initiates molecular signaling pathways that promote glucose uptake in cells and glycogen synthesis. Insulin binding to IR induces phosphorylation of intracellular tyrosine kinase domains and recruitment of multiple SH2 and SH3 domain-containing intracellular proteins that serve as signaling intermediates for pleiotropic effects of insulin. The human insulin receptor gene maps to chromosome 19p13.3-p13.2 and encodes a 1382 amino acid protein that cleaves to form α and β subunits. Type 1 diabetes is an auto-immune condition of the endocrine pancreas that results in destruction of insulin secreting cells and a progressive loss in insulin-sensitive glucose uptake by cells. Type 2 diabetes is a condition where cells become resistant to insulin action. |
| Conjucates | Unconjugated |
| Immunogen | A synthesized peptide: within human Insulin receptor aa 930-970 |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID |
| Molecular Weight | Theoretical: 156 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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