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Anti-gp130/IL6ST Antibody (2B824)
(Synonyms: interleukin 6 signal transducer, IL-6RB, GP130, CDW130, CD130) Copy Product Info
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Synonyms: interleukin 6 signal transducer, IL-6RB, GP130, CDW130, CD130
Catalog No. TMAC-00654 Copy Product Info
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Anti-gp130/IL6ST Antibody (2B824) is a Mouse antibody targeting gp130/IL6ST. Anti-gp130/IL6ST Antibody (2B824) can be used in ICC,IHC,WB.
Anti-gp130/IL6ST Antibody
(2B824)
(2B824)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $296 | 7-10 days | 7-10 days | |
| 100 μL | $427 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-gp130/IL6ST Antibody (2B824) is a Mouse antibody targeting gp130/IL6ST. Anti-gp130/IL6ST Antibody (2B824) can be used in ICC,IHC,WB. |
| Synonyms | interleukin 6 signal transducer, IL-6RB, GP130, CDW130, CD130 |
| Clone | 2B824 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC: 1:50-200; ICC: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProG affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates Janus kinases. That causes phosphorylation of IL6ST tyrosine residues which in turn activates STAT3. Mediates signals which regulate immune response, hematopoiesis, pain control and bone metabolism. Has a role in embryonic development. Does not bind IL6. Essential for survival of motor and sensory neurons and for differentiation of astrocytes. Required for expression of TRPA1 in nociceptive neurons. Required for the maintenance of PTH1R expression in the osteoblast lineage and for the stimulation of PTH-induced osteoblast differentiation. Required for normal trabecular bone mass and cortical bone composition. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 103 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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