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Lipoic acid

Name: Lipoic acid
Brand: TargetMol
SKU: T22235
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T22235Cas No. 1200-22-2

Alias R-(+)-Thioctic acid, (R)-(+)-α-Lipoic acid, (R)-(+)-1,2-Dithiolane-3-pentanoic acid

Lipoic acid (R-(+)-Thioctic acid) is an organosulfur compound derived from octanoic acid. It is made in animals normally, and is essential for aerobic metabolism.

Lipoic acid

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Purity: 99.79%

Catalog No. T22235Alias R-(+)-Thioctic acid, (R)-(+)-α-Lipoic acid, (R)-(+)-1,2-Dithiolane-3-pentanoic acidCas No. 1200-22-2

Lipoic acid (R-(+)-Thioctic acid) is an organosulfur compound derived from octanoic acid. It is made in animals normally, and is essential for aerobic metabolism.

Pack Size	Price	Availability
500 mg	$29	In Stock
5 g	$58	In Stock
10 g	$83	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock

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Batch Information

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Purity:99.79%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Lipoic acid (R-(+)-Thioctic acid) is an organosulfur compound derived from octanoic acid. It is made in animals normally, and is essential for aerobic metabolism.
Synonyms	R-(+)-Thioctic acid, (R)-(+)-α-Lipoic acid, (R)-(+)-1,2-Dithiolane-3-pentanoic acid

Chemical Properties

Molecular Weight	206.33
Formula	C₈H₁₄O₂S₂
Cas No.	1200-22-2
Smiles	C(CCCC(O)=O)[C@@H]1CCSS1
Relative Density.	1.218 g/cm3 (Predicted)
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 242 mg/mL (1172.88 mM), Sonication is recommended.

H2O: < 0.1 mg/mL (insoluble)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.8466 mL	24.2330 mL	48.4660 mL	242.3302 mL
5 mM	0.9693 mL	4.8466 mL	9.6932 mL	48.4660 mL
10 mM	0.4847 mL	2.4233 mL	4.8466 mL	24.2330 mL
20 mM	0.2423 mL	1.2117 mL	2.4233 mL	12.1165 mL
50 mM	0.0969 mL	0.4847 mL	0.9693 mL	4.8466 mL
100 mM	0.0485 mL	0.2423 mL	0.4847 mL	2.4233 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc