Anti-POU5F1 Polyclonal Antibody

Name: Anti-POU5F1 Polyclonal Antibody
Brand: TargetMol
SKU: TMAB-01562
Rating: 4.5 (1 reviews)

(Synonyms: transcription factor 1, POU5F1, POU domain, class 5, transcription factor 1, OTF3, Octamer-binding transcription factor 3 (OTF-3), Octamer-binding protein 4 (Oct-4), Octamer-binding protein 3 (Oct-3), class 5) Copy Product Info

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Synonyms: transcription factor 1, POU5F1, POU domain, class 5, transcription factor 1, OTF3, Octamer-binding transcription factor 3 (OTF-3), Octamer-binding protein 4 (Oct-4), Octamer-binding protein 3 (Oct-3), class 5

Catalog No. TMAB-01562 Copy Product Info

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Anti-POU5F1 Polyclonal Antibody is a Rabbit antibody targeting POU5F1. Anti-POU5F1 Polyclonal Antibody can be used in FCM,WB.

Anti-POU5F1 Polyclonal Antibody

Pack Size	Price	USA Stock	Global Stock
50 μL	$221	7-10 days	7-10 days
100 μL	$373	7-10 days	7-10 days
200 μL	$528	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-POU5F1 Polyclonal Antibody is a Rabbit antibody targeting POU5F1. Anti-POU5F1 Polyclonal Antibody can be used in FCM,WB.
Synonyms	transcription factor 1, POU5F1, POU domain, class 5, transcription factor 1, OTF3, Octamer-binding transcription factor 3 (OTF-3), Octamer-binding protein 4 (Oct-4), Octamer-binding protein 3 (Oct-3), class 5
Ig Type	IgG
Reactivity	Human,Mouse,Rat (predicted:Dog,Pig,Cow)

Application	FCM WB
Recommended Dose	WB: 1:500-2000; FCM: 1ug/Test
Antibody Type	Polyclonal
Host Species	Rabbit
Subcellular Localization	Nucleus.Note=Expressed in a diffuse and slightly punctuate pattern.
Tissue Specificity	Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues.
Construction	Polyclonal Antibody
Purification	Protein A purified
Appearance	Liquid
Formulation	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration	1 mg/mL
Research Background	This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq].

Antigen Details

Immunogen	KLH conjugated synthetic peptide: human OCT4
Antigen Species	Human
Gene Name	POU5F1
Gene ID	5460
Protein Name	POU domain, class 5, transcription factor 1
Uniprot ID	Q01860
Biology Area	DNA / RNA binding,POU,Transcription Factors
Function	Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.