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Quipazine

Catalog No. T73341 Copy Product Info
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Quipazine is a non-selective 5-HT receptor agonist. It stimulates central serotonin receptors to induce serotonin syndrome in animal models, utilized for studying behavioral regulation and sleep cycle control.

Quipazine

Copy Product Info
🥰Excellent
Catalog No. T73341

Quipazine is a non-selective 5-HT receptor agonist. It stimulates central serotonin receptors to induce serotonin syndrome in animal models, utilized for studying behavioral regulation and sleep cycle control.

Quipazine
Cas No. 4774-24-7
Pack SizePriceUSA StockGlobal StockQuantity
25 mg$301-2 weeks1-2 weeks
50 mg$401-2 weeks1-2 weeks
1 mL x 10 mM (in DMSO)$391-2 weeks1-2 weeks
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Quipazine is a non-selective 5-HT receptor agonist. It stimulates central serotonin receptors to induce serotonin syndrome in animal models, utilized for studying behavioral regulation and sleep cycle control.
Targets&IC50
5-HT3 Receptor:1.4 nM (Ki)
In vitro
Quipazine efficiently displaces 5-HT3R ligands in rat brain [4].
Quipazine can act as a photosensitizer to block SARS-CoV-2 main protease [2].
In vivo
Quipazine (2.5-7.5 mg/kg i.p.) significantly alters dietary self-selection of macronutrients in rats [1].
Chemical Properties
Molecular Weight213.28
FormulaC13H15N3
Cas No.4774-24-7
SmilesN=1C=2C=CC=CC2C=CC1N3CCNCC3
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 6.6 mg/mL (30.95 mM), Sonication is recommmended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.6887 mL23.4434 mL46.8867 mL234.4336 mL
5 mM0.9377 mL4.6887 mL9.3773 mL46.8867 mL
10 mM0.4689 mL2.3443 mL4.6887 mL23.4434 mL
20 mM0.2344 mL1.1722 mL2.3443 mL11.7217 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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