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Gremlin-1 Protein, Mouse/Rat, Recombinant (His & Myc)

(Synonyms: Gremlin-1, Grem1, Drm, Down-regulated in Mos-transformed cells protein, Cysteine knot superfamily 1, BMP antagonist 1, Cktsf1b1) Copy Product Info

Synonyms: Gremlin-1, Grem1, Drm, Down-regulated in Mos-transformed cells protein, Cysteine knot superfamily 1, BMP antagonist 1, Cktsf1b1

Catalog No. TMPH-03308 Copy Product Info
Gremlin-1 Protein, Mouse/Rat, Recombinant (His & Myc) is expressed in HEK293.
Gremlin-1 Protein, Mouse/Rat, Recombinant (His & Myc)
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Pack SizePriceUSA StockGlobal StockQuantity
5 µg$21920 days20 days
10 µg$36520 days20 days
20 µg$61320 days20 days
50 µg$1,16020 days20 days
100 µg$1,89020 days20 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Gremlin-1 Protein, Mouse/Rat, Recombinant (His & Myc) is expressed in HEK293.
Species
Rat/Mouse
Expression System
HEK293 Cells
TagN-10xHis, C-Myc
Accession NumberO35793/O70326
Amino AcidKKKGSQGAIPPPDKAQHNDSEQTQSPPQPGSRTRGRGQGRGTAMPGEEVLESSQEALHVTERKYLKRDWCKTQPLKQTIHEEGCNSRTIINRFCYGQCNSFYIPRHIRKEEGSFQSCSFCKPKKFTTMMVTLNCPELQPPTKKKRVTRVKQCRCISIDLD
Construction25-184 aa
Protein Purity
> 85% as determined by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationTris-based buffer, 50% glycerol
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
SynonymsGremlin-1, Grem1, Drm, Down-regulated in Mos-transformed cells protein, Cysteine knot superfamily 1, BMP antagonist 1, Cktsf1b1
Research Background
Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner. Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro). Acts as inhibitor of monocyte chemotaxis. Can inhibit the growth or viability of normal cells but not transformed cells when is overexpressed.
Chemical Properties
Molecular Weight22.2 kDa (predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: Gremlin-1 Protein, Mouse/Rat, Recombinant (His & Myc) chemical structure | Gremlin-1 Protein, Mouse/Rat, Recombinant (His & Myc) molecular weight