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Gremlin-1 Protein, Rat, Recombinant (His & Myc)

Gremlin-1 Protein, Rat, Recombinant (His & Myc)
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Gremlin-1 Protein, Rat, Recombinant (His & Myc)

Catalog No. TMPH-03308
Gremlin-1 Protein, Rat, Recombinant (His & Myc) is expressed in HEK293.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
20 μg$61420 days
100 μg$1,72020 days
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Biological Description

Description
Gremlin-1 Protein, Rat, Recombinant (His & Myc) is expressed in HEK293.
Species
Rat
Expression System
HEK293 Cells
TagN-10xHis, C-Myc
Accession NumberO35793
Synonyms
Down-regulated in Mos-transformed cells protein,Gremlin-1,Cysteine knot superfamily 1, BMP antagonist 1,Grem1
Amino Acid
KKKGSQGAIPPPDKAQHNDSEQTQSPPQPGSRTRGRGQGRGTAMPGEEVLESSQEALHVTERKYLKRDWCKTQPLKQTIHEEGCNSRTIINRFCYGQCNSFYIPRHIRKEEGSFQSCSFCKPKKFTTMMVTLNCPELQPPTKKKRVTRVKQCRCISIDLD
Construction
25-184 aa
Protein Purity
> 85% as determined by SDS-PAGE.
Molecular Weight22.2 kDa (predicted)
FormulationTris-based buffer, 50% glycerol
Reconstitution
A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background
Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner. Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro). Acts as inhibitor of monocyte chemotaxis. Can inhibit the growth or viability of normal cells but not transformed cells when is overexpressed.

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please read the User Guide of Recombinant Proteins for more specific information.