PGA4 Protein, Human, Recombinant (hFc)

Name: PGA4 Protein, Human, Recombinant (hFc)
Brand: TargetMol
SKU: TMPY-02385
Rating: 4.5 (1 reviews)

(Synonyms: PGA5, PGA4, PGA3, pepsinogen 4, group I (pepsinogen A), FLJ77962, FLJ58952) Copy Product Info

Synonyms: PGA5, PGA4, PGA3, pepsinogen 4, group I (pepsinogen A), FLJ77962, FLJ58952

Catalog No. TMPY-02385 Copy Product Info

PGA4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 67.3 kDa and the accession number is A0A1S5UZ02.

Pack Size	Price	USA Stock	Global Stock
5 µg	$93	7-10 days	7-10 days
10 µg	$152	7-10 days	7-10 days
20 µg	$248	7-10 days	7-10 days
50 µg	$577	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK(Dnp)-NH2. The specific activity is > 3000 pmoles/min/μg. (Activation description: The enzyme achieves its activity under acidic pH)
Description	PGA4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 67.3 kDa and the accession number is A0A1S5UZ02.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	P0DJD7
Construction	A DNA sequence encoding the human PGA4 (NP_001073276.1) (Met 1-Ala 388) was fused with the Fc region of human IgG1 at the C-terminus. Predicted N terminal: Ile 16
Protein Purity	> 80 % as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonyms	PGA5, PGA4, PGA3, pepsinogen 4, group I (pepsinogen A), FLJ77962, FLJ58952
Research Background	PGA4 (Pepsinogen 4, group I), or Pepsinogen A, is a member of the peptidase A1 family. Pepsin is expressed as a pro-form zymogen, pepsinogen, whose primary structure has an additional 44 amino acids. Pepsin is stored as pepsinogen so it will only be released when needed, and does not digest the body's own proteins in the stomach's lining. Five types of zymogens of pepsins, gastric digestive proteinases, are known: pepsinogens A, B, and F, progastricsin, and prochymosin. There are two major groups of pepsinogen, namely pepsinogen A (PGA) and pepsinogen C (PGC) (or progastricsin), and each frequently has isozymogens. The PGA3, PGA4 and PGA5 genes encode identical human pepsinogen A enzymes.

Chemical Properties

Molecular Weight

67.3 kDa (predicted); 65-70 kDa (reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.