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Anti-SEMA3A Polyclonal Antibody is a Rabbit antibody targeting SEMA3A. Anti-SEMA3A Polyclonal Antibody can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $221 | 7-10 days | |
100 μL | $374 | 7-10 days | |
200 μL | $528 | 7-10 days |
Description | Anti-SEMA3A Polyclonal Antibody is a Rabbit antibody targeting SEMA3A. Anti-SEMA3A Polyclonal Antibody can be used in WB. |
Synonyms | Semaphorin-3A, Semaphorin III (Sema III), Sema3a |
Ig Type | IgG |
Reactivity | Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Horse,Rabbit,Sheep) |
Verified Activity | Sample: Lung (Mouse) Lysate at 40 μg Primary: Anti-Sema3A (TMAB-01673) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 86 kDa Observed band size: 86 kDa ![]() |
Application | |
Recommended Dose | WB: 1:500-2000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Secreted. |
Tissue Specificity | Expressed at relatively high levels in brain and muscle, moderate levels in lung, bursa, and heart and virtually absent in liver. Collapsin-1, -2, -3, and -5 bind to overlapping but distinct axon tracts. |
Construction | Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Concentration | 1 mg/mL |
Research Background | This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease. |
Immunogen | KLH conjugated synthetic peptide: mouse Sema3A |
Antigen Species | Mouse |
Gene Name | SEMA3A |
Gene ID | |
Protein Name | Semaphorin-3A |
Uniprot ID | |
Biology Area | Cardiac arrhythmias,Transcription factors/regulators,Hypertrophy,Axonal Guidance Proteins |
Function | Plays a role in growth cones guidance. May function to pattern sensory projections by selectively repelling axons that normally terminate dorsally. Involved in the development of the olfactory system and in neuronal control of puberty. |
Molecular Weight | Theoretical: 86 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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