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Anti-Carboxypeptidase A2 Antibody (6I522) is a Mouse antibody targeting Carboxypeptidase A2. Anti-Carboxypeptidase A2 Antibody (6I522) can be used in ELISA,IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $198 | 7-10 days |
Description | Anti-Carboxypeptidase A2 Antibody (6I522) is a Mouse antibody targeting Carboxypeptidase A2. Anti-Carboxypeptidase A2 Antibody (6I522) can be used in ELISA,IHC-P. |
Alias | CPA2, carboxypeptidase A2 |
Ig Type | Monoclonal Mouse IgG2a |
Clone | 6I522 |
Reactivity | Human |
Verified Activity | Immunochemical staining of human CPA2 in human pancreas (from two donors) with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). Positive staining was localized to pancreatic acinus. |
Application | ELISA,IHC-P |
Recommended Dose | ELISA: 1:1000-1:2000; IHC-P: 1:50-1:200 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CPA2 (rh CPA2; TMPY-00726; NP_001859.1; Met 1-Tyr 417). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Carboxypeptidase A2 ( CPA2 ) is a secreted pancreatic procarboxy -peptidase, and cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group. The hydrolytic action of CPA2 was identified with a preference towards long substrates with aromatic amino acids in their C-terminal end, particularly tryptophan. CPA2 comprises a signal peptide, a pro region and a mature chain, and can be activated after cleavage of the pro peptide. Three different forms of human pancreatic procarboxypeptidase A have been isolated, and the A1 and A2 forms are always secreted as monomeric proteins with different biochemical properties. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human CPA2 protein (TMPY-00726) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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