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(-)-α-Terpineol

Name: (-)-α-Terpineol
Brand: TargetMol
SKU: T7468
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T7468Cas No. 10482-56-1

Alias α-Terpineol

(-)-α-Terpineol has antitumour, anti-inflammatory, and antimicrobial activities, it inhibits the growth of tumour cells through a mechanism that involves inhibition of the NF-kappaB pathway

(-)-α-Terpineol

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Purity: 99.85%

Catalog No. T7468Alias α-TerpineolCas No. 10482-56-1

(-)-α-Terpineol has antitumour, anti-inflammatory, and antimicrobial activities, it inhibits the growth of tumour cells through a mechanism that involves inhibition of the NF-kappaB pathway

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
25 g	$30	-	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.85%

Appearance:Solid

Color:White

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COA HNMR LCMS

Product Introduction

(-)-α-Terpineol AI Summary

(-)-α-Terpineol exhibits a variety of biological activities across different systems. It has cicatrizant activity in mice, showing wound healing properties with an effective dose (ED50) of 240.0 mg/kg as measured by tensile strength. Additionally, it inhibits growth of mouse 3T3 cells with a GI50 of 17.0 ug/mL. It has antioxidant properties, with a DPPH radical scavenging EC50 value of 146.3 ug/mL, indicating its potential to neutralize free radicals. The compound demonstrates antimicrobial activity against a range of microorganisms, including Propionibacterium acnes, Streptococcus mutans, and Pityrosporum ovale, with MICs of 100.0, 400.0, and 400.0 ug/mL, respectively, as well as antifungal activity against Aspergillus flavus with complete inhibition at 60 uL and 20 uL concentrations. In terms of acaricidal activity, (-)-α-Terpineol is highly effective against Psoroptes cuniculi, exhibiting activity levels from 73.3% to 100.0% in various assays. It also shows insecticidal capabilities against Leptinotarsa decemlineata (Colorado potato beetle) and Musca domestica (house fly), with varying mortality rates and an LD50 of 137.5 ug for house flies. Furthermore, it exhibits anti-mite activity against Tetranychus urticae with LC50 values ranging from 36.1 to 44.2 microg/cm3. In specific enzymatic assays, (-)-α-Terpineol shows activity related to UGT1A4 but not UGT1A1, with an activity rate of 25.0 pm/min/mg. It also possesses a log K value of 0.82, suggesting a balance between hydrophobic and hydrophilic properties. This broad-spectrum bioactivity makes (-)-α-Terpineol a compound of interest for multiple applications including wound healing, antioxidation, antimicrobial, acaricidal, and insecticidal potential..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	(-)-α-Terpineol has antitumour, anti-inflammatory, and antimicrobial activities, it inhibits the growth of tumour cells through a mechanism that involves inhibition of the NF-kappaB pathway
Synonyms	α-Terpineol

Chemical Properties

Molecular Weight	154.25
Formula	C₁₀H₁₈O
Cas No.	10482-56-1
Smiles	CC1=CC[C@H](CC1)C(C)(C)O
Relative Density.	0.93 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 22.5 mg/mL (145.87 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (12.97 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.4830 mL	32.4149 mL	64.8298 mL	324.1491 mL
5 mM	1.2966 mL	6.4830 mL	12.9660 mL	64.8298 mL
10 mM	0.6483 mL	3.2415 mL	6.4830 mL	32.4149 mL
20 mM	0.3241 mL	1.6207 mL	3.2415 mL	16.2075 mL
50 mM	0.1297 mL	0.6483 mL	1.2966 mL	6.4830 mL
100 mM	0.0648 mL	0.3241 mL	0.6483 mL	3.2415 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc