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Anti-SLAMF6 Antibody-PE (4Z355)
🥰Excellent
Catalog No. TMAY-02159P
Anti-SLAMF6 Antibody-PE (4Z355) is a PE-conjugated Rabbit antibody targeting SLAMF6. Anti-SLAMF6 Antibody-PE (4Z355) can be used in FCM.
Anti-SLAMF6 Antibody-PE (4Z355)
Anti-SLAMF6 Antibody-PE (4Z355)
🥰Excellent
Catalog No. TMAY-02159P
Anti-SLAMF6 Antibody-PE (4Z355) is a PE-conjugated Rabbit antibody targeting SLAMF6. Anti-SLAMF6 Antibody-PE (4Z355) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-SLAMF6 Antibody-PE (4Z355) is a PE-conjugated Rabbit antibody targeting SLAMF6. Anti-SLAMF6 Antibody-PE (4Z355) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 4Z355 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human SLAMF6(CD352) expression on human whole blood lymphocytes. Cells were stained with PE-conjugated anti-Human SLAMF6(CD352). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Ly108/SLAMF6 (rh Ly108/SLAMF6; TMPY-01914; Q96DU3-1; Met1-Met226) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly18 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly18 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6 / Ly18 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6 / Ly18 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6 / Ly18 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. |
| Conjucates | PE |
| Others Formats | Unconjugated/APC/FITC |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Human Ly108/SLAMF6 Protein (TMPY-01914) |
| Antigen Species | Human |
| Biology Area | ITIM/ITAM Immunoreceptors and Related Molecules |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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