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Cathepsin X-IN-1

Name: Cathepsin X-IN-1
Brand: TargetMol
SKU: T60812
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T60812Cas No. 2418577-51-0

Cathepsin X-IN-1 (compound 25) is a potent Cathepsin X inhibitor (IC50 = 7.13 μM) that reduces PC-3 cell migration with low cytotoxicity [1].

Cathepsin X-IN-1

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Purity: 99.34%

Catalog No. T60812Cas No. 2418577-51-0

Cathepsin X-IN-1 (compound 25) is a potent Cathepsin X inhibitor (IC50 = 7.13 μM) that reduces PC-3 cell migration with low cytotoxicity [1].

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$35	In Stock	In Stock
5 mg	$58	In Stock	In Stock
10 mg	$98	In Stock	In Stock
25 mg	$197	In Stock	In Stock
50 mg	$323	In Stock	In Stock
100 mg	$466	-	In Stock
200 mg	$648	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.34%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Cathepsin X-IN-1 AI Summary

Cathepsin X-IN-1 exhibits bioactivities related to the inhibition of various cathepsin enzymes, including X, B, L, and S. It demonstrates varying levels of inhibitory effects on these enzymes, as indicated by percentage inhibition values, and shows specific IC50 values for cathepsin X and cathepsin S, suggesting its potency in blocking their activities. Additionally, Cathepsin X-IN-1 displays significant antimigratory activity against human PC-3 cells, highlighting its potential impact on cell migration and invasion..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

Cathepsin X-IN-1 (compound 25) is a potent Cathepsin X inhibitor (IC50 = 7.13 μM) that reduces PC-3 cell migration with low cytotoxicity [1].

Chemical Properties

Molecular Weight	315.35
Formula	C₁₅H₁₃N₃O₃S
Cas No.	2418577-51-0
Smiles	O=C(CSc1nccn1CC#N)c1ccc2OCCOc2c1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90 mg/mL (285.4 mM), Sonication is recommended.

H2O: 4.4 mg/mL (13.95 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1711 mL	15.8554 mL	31.7108 mL	158.5540 mL
5 mM	0.6342 mL	3.1711 mL	6.3422 mL	31.7108 mL
10 mM	0.3171 mL	1.5855 mL	3.1711 mL	15.8554 mL

DMSO

	1mg	5mg	10mg	50mg
20 mM	0.1586 mL	0.7928 mL	1.5855 mL	7.9277 mL
50 mM	0.0634 mL	0.3171 mL	0.6342 mL	3.1711 mL
100 mM	0.0317 mL	0.1586 mL	0.3171 mL	1.5855 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc