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Parsaclisib hydrochloride

Name: Parsaclisib hydrochloride
Brand: TargetMol
SKU: T28297
Rating: 4.5 (1 reviews)

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Catalog No. T28297Cas No. 1995889-48-9

Alias Parsaclisib HCl, INCB50465 HCl, INCB-50465, INCB050465 HCl, INCB-050465, INCB 50465, INCB 050465

Parsaclisib hydrochloride (INCB050465 HCl) is a selectve PI3Kδ inhibitor with antitumor activity. Parsaclisib demonstrates potent activity with IC50 values ranging from 0.2 to 2 nM.

Parsaclisib hydrochloride

😃Good

Catalog No. T28297Alias Parsaclisib HCl, INCB50465 HCl, INCB-50465, INCB050465 HCl, INCB-050465, INCB 50465, INCB 050465Cas No. 1995889-48-9

Parsaclisib hydrochloride (INCB050465 HCl) is a selectve PI3Kδ inhibitor with antitumor activity. Parsaclisib demonstrates potent activity with IC50 values ranging from 0.2 to 2 nM.

Pack Size	Price	Availability
25 mg	$1,230	1-2 weeks
50 mg	$1,610	1-2 weeks
100 mg	$2,570	1-2 weeks

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Product Introduction

Bioactivity

Description	Parsaclisib hydrochloride (INCB050465 HCl) is a selectve PI3Kδ inhibitor with antitumor activity. Parsaclisib demonstrates potent activity with IC50 values ranging from 0.2 to 2 nM.
Targets&IC50	PI3Kδ:1 nM (IC50)
Synonyms	Parsaclisib HCl, INCB50465 HCl, INCB-50465, INCB050465 HCl, INCB-050465, INCB 50465, INCB 050465

Chemical Properties

Molecular Weight	469.34
Formula	C₂₀H₂₃Cl₂FN₆O₂
Cas No.	1995889-48-9
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90 mg/mL (191.76 mM), Sonication is recommended.

H2O: Insoluble

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1307 mL	10.6533 mL	21.3065 mL	106.5326 mL
5 mM	0.4261 mL	2.1307 mL	4.2613 mL	21.3065 mL
10 mM	0.2131 mL	1.0653 mL	2.1307 mL	10.6533 mL
20 mM	0.1065 mL	0.5327 mL	1.0653 mL	5.3266 mL
50 mM	0.0426 mL	0.2131 mL	0.4261 mL	2.1307 mL
100 mM	0.0213 mL	0.1065 mL	0.2131 mL	1.0653 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc