PCSK9 Protein, Macaca nemestrina, Recombinant (His)

Name: PCSK9 Protein, Macaca nemestrina, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-00443
Rating: 4.5 (1 reviews)

(Synonyms: Subtilisin/Kexin-Like Protease PC9, Proprotein Convertase Subtilisin/Kexin Type 9, Proprotein Convertase 9, PCSK9, PC9) Copy Product Info

Synonyms: Subtilisin/Kexin-Like Protease PC9, Proprotein Convertase Subtilisin/Kexin Type 9, Proprotein Convertase 9, PCSK9, PC9

Catalog No. TMPJ-00443 Copy Product Info

Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. PCSK9 also plays a role in the neural development.

PCSK9 Protein, Macaca nemestrina, Recombinant (His)

Pack Size	Price	USA Stock	Global Stock
5 μg	$112	7-10 days	7-10 days
10 μg	$183	7-10 days	7-10 days
20 μg	$292	7-10 days	7-10 days
50 μg	$545	7-10 days	7-10 days
100 μg	$792	7-10 days	7-10 days
200 μg	$1,150	7-10 days	7-10 days
500 μg	$1,900	7-10 days	7-10 days
1 mg	$2,970	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity


Description	Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. PCSK9 also plays a role in the neural development.
Species	Macaca nemestrina
Expression System	HEK293 Cells
Tag	C-6xHis
Accession Number	A8T662
Amino Acid	Gln31-Gln152&Ser153-Gln692
Construction	Gln31-Gln152&Ser153-Gln692
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 0.1M Arg, 0.1M Glu, 20% glycerol, 0.01% tween20, 5% Trehalose, pH 6.0.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Proteins are shipped with blue ice.
Synonyms	Subtilisin/Kexin-Like Protease PC9, Proprotein Convertase Subtilisin/Kexin Type 9, Proprotein Convertase 9, PCSK9, PC9
Research Background

Chemical Properties

Molecular Weight

16-21&55-77 KDa (reducing condition)

Storage & Solubility Information

Storage

Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

PCSK-9PCSK 9PC-9PC 9

Related Tags: PCSK9 Protein, Macaca nemestrina, Recombinant (His) chemical structure | PCSK9 Protein, Macaca nemestrina, Recombinant (His) molecular weight