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Anti-Phospho-HCLS1 (Tyr378) Polyclonal Antibody

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Catalog No. TMAC-02383

Anti-Phospho-HCLS1 (Tyr378) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HCLS1 (Tyr378). Anti-Phospho-HCLS1 (Tyr378) Polyclonal Antibody can be used in WB,ELISA.

Anti-Phospho-HCLS1 (Tyr378) Polyclonal Antibody

Anti-Phospho-HCLS1 (Tyr378) Polyclonal Antibody

😃Good
Catalog No. TMAC-02383
Anti-Phospho-HCLS1 (Tyr378) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HCLS1 (Tyr378). Anti-Phospho-HCLS1 (Tyr378) Polyclonal Antibody can be used in WB,ELISA.
Pack SizePriceAvailabilityQuantity
50 μL$2187-10 days
100 μL$3177-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-HCLS1 (Tyr378) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HCLS1 (Tyr378). Anti-Phospho-HCLS1 (Tyr378) Polyclonal Antibody can be used in WB,ELISA.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:500-2000; ELISA: 1:40000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
AppearanceLiquid
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Research Backgrounddevelopmental stage:Expressed in early stage of myeloid and erythroid differentiation.,function:Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.,PTM:Phosphorylated by LYN; rapidly after cross-linking of surface IgM on B-cells.,similarity:Contains 1 SH3 domain.,similarity:Contains 4 cortactin repeats.,subunit:Associates with the SH2 and SH3 domains of LCK. Binding to he LCK SH3 domain occurs constitutively, while binding to the LCK SH2 domain occurs only upon TCR stimulation. A similar binding pattern was observed with LYN, but not with FYN in which the FYN SH2 region associates upon TCR stimulation but the FYN SH3 region does not associate regardless of TCR stimulation. Directly associates with HAX1, through binding to its C-terminal region. Interacts with HS1BP3.,tissue specificity:Expressed only in tissues and cells of hematopoietic origin.,
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A synthesized phosphopeptide: human Lck BP-1 around the phosphorylation site of Tyr378
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 78 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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