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Atrial natriuretic factor (1-28) (human, porcine) TFA

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Catalog No. TP3116
Alias Atrial natriuretic peptide (1-28) TFA, Atrial natriuretic factor (1-28) (human, porcine) TFA

Atrial natriuretic factor (1-28) (human, porcine) TFA exhibits antihypertensive activity by promoting sodium and urine excretion. It inhibits the release of adrenocorticotropic hormone (ACTH) and β-endorphin by suppressing pro-opiomelanocortin (POMC) expression. Additionally, it elevates cGMP levels in RMIC cells, with an IC50 of 1.2 nM.

Atrial natriuretic factor (1-28) (human, porcine) TFA

Atrial natriuretic factor (1-28) (human, porcine) TFA

😃Good
Catalog No. TP3116Alias Atrial natriuretic peptide (1-28) TFA, Atrial natriuretic factor (1-28) (human, porcine) TFA
Atrial natriuretic factor (1-28) (human, porcine) TFA exhibits antihypertensive activity by promoting sodium and urine excretion. It inhibits the release of adrenocorticotropic hormone (ACTH) and β-endorphin by suppressing pro-opiomelanocortin (POMC) expression. Additionally, it elevates cGMP levels in RMIC cells, with an IC50 of 1.2 nM.
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1 mg$125 7-10 days
5 mgPreferential7-10 days
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Product Introduction

Bioactivity
Description
Atrial natriuretic factor (1-28) (human, porcine) TFA exhibits antihypertensive activity by promoting sodium and urine excretion. It inhibits the release of adrenocorticotropic hormone (ACTH) and β-endorphin by suppressing pro-opiomelanocortin (POMC) expression. Additionally, it elevates cGMP levels in RMIC cells, with an IC50 of 1.2 nM.
AliasAtrial natriuretic peptide (1-28) TFA, Atrial natriuretic factor (1-28) (human, porcine) TFA
Chemical Properties
Molecular Weight3080.46 (free base)
FormulaC127H205N45O39S3.xC2HF3O2
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice./Shipping at ambient temperature.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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