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Pilocarpine Hydrochloride (NSC 5746 HCl) is an M3-type muscarinic acetylcholine receptor agonist. Pilocarpine Hydrochloride was used to make an experimental model of epilepsy.
Pack Size | Price | Availability | Quantity |
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200 mg | $29 | In Stock |
Description | Pilocarpine Hydrochloride (NSC 5746 HCl) is an M3-type muscarinic acetylcholine receptor agonist. Pilocarpine Hydrochloride was used to make an experimental model of epilepsy. |
Targets&IC50 | Pentoxyresorufin O-dealkylas (mouse liver microsomes):4 μM, testosterone 6 beta-hydroxylase (mouse liver microsomes):> 1 mM, Testosterone 15 alpha-hydroxylase (mouse liver microsomes):6 μM, Coumarin 7-hydroxylase (mouse liver microsomes):6 μM, dimethylnitrosamine N-demethylase (human liver microsomes):10 μM, CYP2A6 (human liver microsomes):5.31μM, Astrocytes:31.86 mM, coumarin 7-hydroxylase (human liver microsomes):6 μM, dimethylnitrosamine N-demethylase (mouse liver microsomes):100 μM |
In vivo | METHODS: To study the effect of Pilocarpine Hydrochloride on salivary secretion, Pilocarpine Hydrochloride (0.5 mg/kg) was injected into rats. RESULTS: The salivary secretion volume of exercise group was significantly higher than that of control group (P<0.01). On the contrary, the Na+ concentration in saliva of the exercise group was significantly lower than that of the control group (P<0.05). [1] |
Synonyms | Pilocarpine HCl, NSC 5746 HCl, (+)-Pilocarpine hydrochloride |
Molecular Weight | 244.72 |
Formula | C11H16N2O2·HCl |
Cas No. | 54-71-7 |
Smiles | Cl.CCC1C(Cc2cncn2C)COC1=O |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||||||||||||
Solubility Information | H2O: 24.5 mg/mL (100.11 mM), Sonication is recommended. DMSO: 4.62 mg/mL (18.86 mM), Sonication is recommended. ![]() | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
DMSO/H2O
H2O
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