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Anti-IFN gamma Antibody-APC (3Z483)
🥰Excellent
Catalog No. TMAY-03419A
Anti-IFN gamma Antibody-APC (3Z483) is a APC-conjugated Rabbit antibody targeting IFN gamma. Anti-IFN gamma Antibody-APC (3Z483) can be used in FCM.
Anti-IFN gamma Antibody-APC (3Z483)
Anti-IFN gamma Antibody-APC (3Z483)
🥰Excellent
Catalog No. TMAY-03419A
Anti-IFN gamma Antibody-APC (3Z483) is a APC-conjugated Rabbit antibody targeting IFN gamma. Anti-IFN gamma Antibody-APC (3Z483) can be used in FCM.
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Chemical Properties
| Description | Anti-IFN gamma Antibody-APC (3Z483) is a APC-conjugated Rabbit antibody targeting IFN gamma. Anti-IFN gamma Antibody-APC (3Z483) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 3Z483 |
| Reactivity | Mouse |
| Verified Activity | Flow cytometric analysis of Mouse Interferon gamma expression on BABL/c splenocytes. BABL/c splenocytes were stimulated for 4-6 hours with PMA and Ionomycin in the presence of GolgiPlug. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with APC-conjugated anti-Mouse Interferon gamma and FITC-conjugated anti-Mouse CD4. The dot plots were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IFN gamma (rM IFN gamma; TMPY-03356; NP_032363.1; Met1-Cys155) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| Research Background | IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. The IFNG monomer consists of a core of six α-helices and an extended unfolded sequence in the C-terminal region. IFN gamma is critical for innate and adaptive immunity against viral and intracellular bacterial infections and tumor control. Aberrant IFN gamma expression is associated with some autoinflammatory and autoimmune diseases. The importance of IFN gamma in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. IFNG also promotes NK cell activity.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | APC |
| Others Formats | Unconjugated/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Mouse IFN gamma Protein (TMPY-03356) |
| Antigen Species | Mouse |
| Biology Area | Neuroinflammation |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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