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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $49 | 5 days | |
5 mg | $79 | Backorder | |
10 mg | $115 | Backorder |
Description | Aminooxy-PEG2-azide, a PEG-based PROTAC linker, is utilized for the synthesis of PROTACs[1] and serves as a non-cleavable 2-unit PEG ADC linker in the synthesis of antibody-drug conjugates (ADCs)[2]. |
In vitro | PROTACs contain two different ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets the desired protein, utilizing the intracellular ubiquitin-proteasome system for selective protein degradation[1]. ADCs are composed of an antibody linked to an ADC cytotoxin via an ADC linker[2]. |
Molecular Weight | 190.2 |
Formula | C6H14N4O3 |
Cas No. | 1043426-13-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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