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Anti-EMMPRIN/CD147 Antibody-FITC (1Z477)
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Catalog No. TMAY-00420F
Alias basigin (Ok blood group)
Anti-EMMPRIN/CD147 Antibody-FITC (1Z477) is a FITC-conjugated Mouse antibody targeting EMMPRIN/CD147. Anti-EMMPRIN/CD147 Antibody-FITC (1Z477) can be used in FCM.
Anti-EMMPRIN/CD147 Antibody-FITC (1Z477)
Anti-EMMPRIN/CD147 Antibody-FITC (1Z477)
😃Good
Catalog No. TMAY-00420FAlias basigin (Ok blood group)
Anti-EMMPRIN/CD147 Antibody-FITC (1Z477) is a FITC-conjugated Mouse antibody targeting EMMPRIN/CD147. Anti-EMMPRIN/CD147 Antibody-FITC (1Z477) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 T | $81 | 7-10 days | |
| 100 T | $175 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: FCM Reactivity: Human |
| Alias | basigin (Ok blood group) |
| Ig Type | Mouse IgG1 |
| Clone | 1Z477 |
| Reactivity | Human |
| Verified Activity | 1. Profile of peripheral blood lymphocytes analyzed by flow cytometry. The fluorescence histograms were derived from events with the forward and side light-scatter characteristics of viable lymphocytes. 2. Immunofluorescence staining of human CD147 in HeLa cells with mouse monoclonal antibody (15 µg/mL). The image showing membrane staining of HeLa cells. Primary antibody (FITC conjugated) was incubated for 1 hour at 37°C. |
| Application | FCM |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD147 / EMMPRIN / Basigin (rh CD147 / EMMPRIN / Basigin; NP_940991.1Met 1-His 205) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| Research Background | CD147/EMMPRIN (Extracellular Matrix Metalloproteinase Inducer), also known as Basigin (BSG), is a transmembrane glycoprotein with different forms resulted from different modes of glycosylation and N-terminal sequence variants. It is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. Recently, CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression. Thus, CD147 and its antibody are used as an effective treatment for malignant cancers. |
| Conjucates | FITC |
| Others Formats | Unconjugated/APC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Protein: Human CD147 protein |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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