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Ac-PAL-AMC

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Catalog No. T37421Cas No. 1431362-79-6

Ac-PAL-AMC is a fluorogenic substrate for the β1i/LMP2 subunit of the 20S immunoproteasome. Upon cleavage, 7-amino-4-methylcoumarin (AMC) is released, and its fluorescence can quantify the activity of the β1i/LMP2 subunit. Ac-PAL-AMC is selective for the immunoproteasome over the constitutive proteasome. AMC displays excitation/emission maxima of 351/430 nm.

Ac-PAL-AMC

Ac-PAL-AMC

😃Good
Catalog No. T37421Cas No. 1431362-79-6
Ac-PAL-AMC is a fluorogenic substrate for the β1i/LMP2 subunit of the 20S immunoproteasome. Upon cleavage, 7-amino-4-methylcoumarin (AMC) is released, and its fluorescence can quantify the activity of the β1i/LMP2 subunit. Ac-PAL-AMC is selective for the immunoproteasome over the constitutive proteasome. AMC displays excitation/emission maxima of 351/430 nm.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$26835 days35 days
5 mg$1,05035 days35 days
10 mg$1,85035 days35 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Ac-PAL-AMC is a fluorogenic substrate for the β1i/LMP2 subunit of the 20S immunoproteasome. Upon cleavage, 7-amino-4-methylcoumarin (AMC) is released, and its fluorescence can quantify the activity of the β1i/LMP2 subunit. Ac-PAL-AMC is selective for the immunoproteasome over the constitutive proteasome. AMC displays excitation/emission maxima of 351/430 nm.
Chemical Properties
Molecular Weight498.57
FormulaC26H34N4O6
Cas No.1431362-79-6
SmilesCC=1C=2C(=CC(NC([C@@H](NC([C@@H](NC(=O)[C@H]3N(C(C)=O)CCC3)C)=O)CC(C)C)=O)=CC2)OC(=O)C1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: Soluble

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Keywords

Ac-PAL-AMCAcPALAMCAc PAL AMC
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