Shopping Cart
Remove All
Your shopping cart is currently empty
Anti-Angiopoietin-1 Antibody (5C751)
Catalog No. TMAY-02623 Copy Product Info
🥰Excellent
Anti-Angiopoietin-1 Antibody (5C751) is a Mouse antibody targeting Angiopoietin-1. Anti-Angiopoietin-1 Antibody (5C751) can be used in ELISA.
Anti-Angiopoietin-1 Antibody (5C751)
Copy Product Info🥰Excellent
Catalog No. TMAY-02623
Anti-Angiopoietin-1 Antibody (5C751) is a Mouse antibody targeting Angiopoietin-1. Anti-Angiopoietin-1 Antibody (5C751) can be used in ELISA.
Anti-Angiopoietin-1 Antibody
(5C751)
(5C751)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $199 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Angiopoietin-1 Antibody (5C751) is a Mouse antibody targeting Angiopoietin-1. Anti-Angiopoietin-1 Antibody (5C751) can be used in ELISA. |
| Ig Type | Mouse IgG2b |
| Clone | 5C751 |
| Reactivity | Human |
| Specificity | Human Angiopoietin-1/ANGPT1 |
| Application | |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Angiopoietin-1 (rh Angiopoietin-1; TMPY-05435; NP_001137.2; Met1-Leu261 and Arg277-Phe498). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In disease, ANGPT2-mediated inhibition of TIE2 in blood vessels is linked to vascular leak, inflammation, and metastasis. Primary congenital glaucoma (PCG) is a leading cause of blindness in children worldwide and is caused by developmental defects in 2 aqueous humor outflow structures, Schlemm's canal (SC) and the trabecular meshwork. We previously identified loss-of-function mutations in the angiopoietin (ANGPT) receptor TEK in families with PCG and showed that ANGPT/TEK signaling is essential for SC development. A role for the major ANGPT ligands in the development of the aqueous outflow pathway. We determined that ANGPT1 is essential for SC development, and that Angpt1-knockout mice form a severely hypomorphic canal with elevated intraocular pressure. By linking ANGPT1 with PCG, these results highlight the importance of ANGPT/TEK signaling in glaucoma pathogenesis and identify a candidate target for therapeutic development. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human Angiopoietin-1 Protein (TMPY-05435) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
Calculator
Preview
Related Tags: buy Anti-Angiopoietin-1 Antibody (5C751) | purchase Anti-Angiopoietin-1 Antibody (5C751) | Anti-Angiopoietin-1 Antibody (5C751) cost | order Anti-Angiopoietin-1 Antibody (5C751)
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.