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Anti-NPSR1 Polyclonal Antibody

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Catalog No. TMAB-01258
Alias VRR1, VRR 1, Vasopressin receptor related receptor 1, PGR14, PGR 14, NPSR1, NPSR 1, NPSR, nps receptor, Neuropeptide S receptor 1, Neuropeptide S receptor, MVTR, GPRA, GPR154, GPR 154, G protein coupled receptor PGR14, G protein coupled receptor for asthma susceptibility, G protein coupled receptor 154, ASRT2

Anti-NPSR1 Polyclonal Antibody is a Rabbit antibody targeting NPSR1. Anti-NPSR1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,ELISA.

Anti-NPSR1 Polyclonal Antibody

Anti-NPSR1 Polyclonal Antibody

😃Good
Catalog No. TMAB-01258Alias VRR1, VRR 1, Vasopressin receptor related receptor 1, PGR14, PGR 14, NPSR1, NPSR 1, NPSR, nps receptor, Neuropeptide S receptor 1, Neuropeptide S receptor, MVTR, GPRA, GPR154, GPR 154, G protein coupled receptor PGR14, G protein coupled receptor for asthma susceptibility, G protein coupled receptor 154, ASRT2
Anti-NPSR1 Polyclonal Antibody is a Rabbit antibody targeting NPSR1. Anti-NPSR1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,ELISA.
Pack SizePriceAvailabilityQuantity
50 μL$2227-10 days
100 μL$3737-10 days
200 μL$5297-10 days
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Product Introduction

Bioactivity
Description
Anti-NPSR1 Polyclonal Antibody is a Rabbit antibody targeting NPSR1. Anti-NPSR1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,ELISA.
SynonymsVRR1, VRR 1, Vasopressin receptor related receptor 1, PGR14, PGR 14, NPSR1, NPSR 1, NPSR, nps receptor, Neuropeptide S receptor 1, Neuropeptide S receptor, MVTR, GPRA, GPR154, GPR 154, G protein coupled receptor PGR14, G protein coupled receptor for asthma susceptibility, G protein coupled receptor 154, ASRT2
Ig Type
IgG
Reactivity
(predicted:Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep)
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell Membrane and Cytoplasmic
Tissue SpecificityUbiquitous. Isoform 1 is predominantly expressed in smooth muscle. Isoform 4 is predominantly expressed in epithelial cells. In bronchial biopsies, it is expressed in smooth muscle cells of asthma patients, but not in control patients; whereas in epitheli
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundG protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR154 (G-protein coupled receptor 154), also known as NPSR1 (neuropeptide S receptor), GPRA (G-protein coupled receptor for asthma susceptibility) or PGR14, is a 371 amino acid protein that is thought to play a role in autocrine or paracrine signaling pathways. Ubiquitously expressed, GPR154 exists as nine alternatively spliced isoforms. Defects in the gene encoding GPR154 is the cause of asthma-related traits type 2 (ASRT2).
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human NPSR1
Antigen Species
Human
Gene Name
NPSR1
Gene ID
Protein Name
Neuropeptide S receptor
Uniprot ID
Biology Area
Macrophage / Inflamm.,More GPCR,GPCR
Function
Neuropeptide S receptor 1 (GPR154) is a receptor for Neuropeptide S. It is expressed on the epithelia of several organs including the intestine, and appears to be upregulated in inflammation. It is upregulated in macrophages after antigen challenge and is involved in the pathogenesis of asthma and other IgE-mediated diseases.
Chemical Properties
Molecular WeightTheoretical: 43 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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