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Synonyms: TRAP, SPENCDI, acid phosphatase 5, tartrate resistant
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
| Description | Anti-ACP5 Polyclonal Antibody 2 is a Rabbit antibody targeting ACP5. Anti-ACP5 Polyclonal Antibody 2 can be used in FCM. |
| Synonyms | TRAP, SPENCDI, acid phosphatase 5, tartrate resistant |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Pig) |
| Application | |
| Recommended Dose | FCM: 2ug/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Lysosome. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes an iron containing glycoprotein which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. [provided by RefSeq, Aug 2008] |
| Immunogen | KLH conjugated synthetic peptide: human TRAP5 |
| Antigen Species | Human |
| Gene Name | ACP5 |
| Gene ID | |
| Protein Name | Tartrate-resistant acid phosphatase type 5 |
| Uniprot ID | |
| Biology Area | Phosphatases,Phosphatases,Other Metabolism Assay |
| Function | Defects in ACP5 are the cause of spondyloenchondrodysplasia with immune dysregulation (SPENCDI) [MIM:607944]. A disease characterized by vertebral and metaphyseal dysplasia, spasticity with cerebral calcifications, and strong predisposition to autoimmune diseases. The skeletal dysplasia is characterized by radiolucent and irregular spondylar and metaphyseal lesions that represent islands of chondroid tissue within bone. Note=ACP5 inactivating mutations result in a functional excess of phosphorylated osteopontin causing deregulation of osteopontin signaling and consequential autoimmune disease. |
| Molecular Weight | Theoretical: 34 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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