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PRE-084 hydrochloride

Name: PRE-084 hydrochloride
Brand: TargetMol
SKU: T3198L
Price: 37 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T3198LCas No. 75136-54-8

PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay).

PRE-084 hydrochloride

🥰Excellent

Purity: 99.54%

Catalog No. T3198LCas No. 75136-54-8

PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay).

Pack Size	Price	Availability
5 mg	$37	In Stock
10 mg	$59	In Stock
25 mg	$123	In Stock
50 mg	$218	In Stock
100 mg	$389	In Stock
200 mg	$595	In Stock
1 mL x 10 mM (in DMSO)	$66	In Stock

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Batch Information

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Purity:99.54%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description

PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay).

Chemical Properties

Molecular Weight	353.88
Formula	C₁₉H₂₈ClNO₃
Cas No.	75136-54-8
Smiles	Cl.O=C(OCCN1CCOCC1)C1(CCCCC1)c1ccccc1
Relative Density.	no data available
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 31 mg/mL (87.6 mM), Sonication is recommended.

H2O: 35.4 mg/mL (100.03 mM), Sonication and heating are recommended.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	2.8258 mL	14.1291 mL	28.2582 mL	141.2908 mL
5 mM	0.5652 mL	2.8258 mL	5.6516 mL	28.2582 mL
10 mM	0.2826 mL	1.4129 mL	2.8258 mL	14.1291 mL
20 mM	0.1413 mL	0.7065 mL	1.4129 mL	7.0645 mL
50 mM	0.0565 mL	0.2826 mL	0.5652 mL	2.8258 mL

H2O

	1mg	5mg	10mg	50mg
100 mM	0.0283 mL	0.1413 mL	0.2826 mL	1.4129 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc