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Anti-MYBBP1A Antibody (6F573)

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Catalog No. TMAH-00791
Alias P160, MYBBP 1A, Myb-binding protein 1A

Anti-MYBBP1A Antibody (6F573) is an antibody targeting MYBBP1A. Anti-MYBBP1A Antibody (6F573) can be used in ELISA, IHC, IF.

Anti-MYBBP1A Antibody (6F573)

Anti-MYBBP1A Antibody (6F573)

😃Good
Catalog No. TMAH-00791Alias P160, MYBBP 1A, Myb-binding protein 1A
Anti-MYBBP1A Antibody (6F573) is an antibody targeting MYBBP1A. Anti-MYBBP1A Antibody (6F573) can be used in ELISA, IHC, IF.
Pack SizePriceAvailabilityQuantity
50 μL$209 7-10 days
100 μL$348 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Recombinant Rabbit Monoclonal

Application: ELISA, IHC, IF

Reactivity: Human
AliasP160, MYBBP 1A, Myb-binding protein 1A
Ig Type
Rabbit IgG
Clone
6F573
Reactivity
Human
Verified Activity
1. IHC image of TMAH-00791 diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
2. Immunofluorescence staining of HepG2 Cells with TMAH-00791 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).
Application
ELISA, IHC, IF
Recommended Dose
IHC:1:50-1:200; IF:1:20-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationCytoplasm. Nucleus. Nucleus, nucleolus.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundMay activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2. Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter. Has a role in rRNA biogenesis together with PWP1.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human MYBBP1A
Antigen Species
Human
Gene ID
10514
Uniprot ID
Biology Area
Epigenetics and Nuclear Signaling, Cancer, Signal transduction
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Sci Citations

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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