Anti-R-Spondin 2/RSPO2 Polyclonal Antibody

Name: Anti-R-Spondin 2/RSPO2 Polyclonal Antibody
Brand: TargetMol
SKU: TMAB-01637
Rating: 4.5 (1 reviews)

(Synonyms: R-spondin 2, CRISTIN2) Copy Product Info

🥰Excellent

Synonyms: R-spondin 2, CRISTIN2

Catalog No. TMAB-01637 Copy Product Info

🥰Excellent

Anti-R-Spondin 2/RSPO2 Polyclonal Antibody is a Rabbit antibody targeting R-Spondin 2/RSPO2. Anti-R-Spondin 2/RSPO2 Polyclonal Antibody can be used in WB.

Anti-R-Spondin 2/RSPO2 Polyclonal Antibody

Pack Size	Price	USA Stock	Global Stock
50 μL	$222	7-10 days	7-10 days
100 μL	$372	7-10 days	7-10 days
200 μL	$529	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Resource Download

Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-R-Spondin 2/RSPO2 Polyclonal Antibody is a Rabbit antibody targeting R-Spondin 2/RSPO2. Anti-R-Spondin 2/RSPO2 Polyclonal Antibody can be used in WB.
Synonyms	R-spondin 2, CRISTIN2
Ig Type	IgG
Reactivity	Mouse,Rat (predicted:Human,Dog,Pig,Cow)

Application	WB
Recommended Dose	WB: 1:500-2000
Antibody Type	Polyclonal
Host Species	Rabbit
Subcellular Localization	Secreted
Construction	Polyclonal Antibody
Purification	Protein A purified
Appearance	Liquid
Formulation	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration	1 mg/mL
Research Background	R-spondins (RSPOs), such as RSPO2, are secreted proteins that regulate beta-catenin (CTNNB1; MIM 116806) signaling (Kim et al., 2006 [PubMed 16357527]).[supplied by OMIM, Mar 2008]

Antigen Details

Immunogen	KLH conjugated synthetic peptide: human RSPO2
Antigen Species	Human
Gene Name	RSPO2
Gene ID	340419
Protein Name	R-spondin-2
Uniprot ID	Q6UXX9
Function	Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Probably also acts as a ligand for frizzled and LRP receptors.