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Anti-R-Spondin 2/RSPO2 Polyclonal Antibody
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Catalog No. TMAB-01637
Alias R-spondin 2, CRISTIN2
Anti-R-Spondin 2/RSPO2 Polyclonal Antibody is a Rabbit antibody targeting R-Spondin 2/RSPO2. Anti-R-Spondin 2/RSPO2 Polyclonal Antibody can be used in WB.
Anti-R-Spondin 2/RSPO2 Polyclonal Antibody
Anti-R-Spondin 2/RSPO2 Polyclonal Antibody
😃Good
Catalog No. TMAB-01637Alias R-spondin 2, CRISTIN2
Anti-R-Spondin 2/RSPO2 Polyclonal Antibody is a Rabbit antibody targeting R-Spondin 2/RSPO2. Anti-R-Spondin 2/RSPO2 Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $222 | 7-10 days | |
| 100 μL | $372 | 7-10 days | |
| 200 μL | $529 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-R-Spondin 2/RSPO2 Polyclonal Antibody is a Rabbit antibody targeting R-Spondin 2/RSPO2. Anti-R-Spondin 2/RSPO2 Polyclonal Antibody can be used in WB. |
| Synonyms | R-spondin 2, CRISTIN2 |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Dog,Pig,Cow) |
| Verified Activity | Sample: Lane 1: Mouse Cerebrum tissue lysates Lane 2: Mouse Large intestine tissue lysates Lane 3: Mouse Placenta tissue lysates Lane 4: Mouse Liver tissue lysates Lane 5: Mouse Lung tissue lysates Lane 6: Rat Cerebrum tissue lysates Lane 7: Rat Large intestine tissue lysates Lane 8: Rat Placenta tissue lysates Lane 9: Rat Liver tissue lysates Lane 10: Rat Lung tissue lysates Primary: Anti-RSPO2 (TMAB-01637) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 26 kDa Observed band size: 28 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | R-spondins (RSPOs), such as RSPO2, are secreted proteins that regulate beta-catenin (CTNNB1; MIM 116806) signaling (Kim et al., 2006 [PubMed 16357527]).[supplied by OMIM, Mar 2008] |
| Immunogen | KLH conjugated synthetic peptide: human RSPO2 |
| Antigen Species | Human |
| Gene Name | RSPO2 |
| Gene ID | |
| Protein Name | R-spondin-2 |
| Uniprot ID | |
| Function | Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Probably also acts as a ligand for frizzled and LRP receptors. |
| Molecular Weight | Theoretical: 26 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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