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5-hydroxy Omeprazole (Synonyms: Hydroxyomeprazole)

Name: 5-hydroxy Omeprazole
Brand: TargetMol
SKU: T37659
Rating: 4.5 (1 reviews)

Catalog No. T37659 Copy Product Info

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5-hydroxy Omeprazole is one of the major metabolites of the proton pump inhibitor omeprazole in the body; it is formed by hydroxylation catalyzed by the CYP2C19 and CYP3A4 enzymes in the liver. 5-hydroxy Omeprazole can be used in pharmacokinetic studies.

5-hydroxy Omeprazole

Copy Product Info

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Catalog No. T37659

Synonyms Hydroxyomeprazole

Cas No. 92340-57-3

Pack Size	Price	USA Stock	Global Stock	Quantity
500 μg	$910	35 days	35 days
1 mg	$1,330	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Appearance:Solid

Color:White

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COA

Product Introduction

Bioactivity

Description	5-hydroxy Omeprazole is one of the major metabolites of the proton pump inhibitor omeprazole in the body; it is formed by hydroxylation catalyzed by the CYP2C19 and CYP3A4 enzymes in the liver. 5-hydroxy Omeprazole can be used in pharmacokinetic studies.
Synonyms	Hydroxyomeprazole

Chemical Properties

Molecular Weight	361.42
Formula	C₁₇H₁₉N₃O₄S
Cas No.	92340-57-3
Smiles	O=S(C1=NC=2C=C(OC)C=CC2N1)CC3=NC=C(C(OC)=C3C)CO

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 1 mg/mL (2.77 mM), Sonication is recommended.

DMF: 10 mg/mL (27.67 mM), Sonication is recommended.

DMSO: 5 mg/mL (13.83 mM), Sonication is recommended.

Solution Preparation Table

Ethanol/DMSO/DMF

	1mg	5mg	10mg	50mg
1 mM	2.7669 mL	13.8343 mL	27.6686 mL	138.3432 mL

DMSO/DMF

	1mg	5mg	10mg	50mg
5 mM	0.5534 mL	2.7669 mL	5.5337 mL	27.6686 mL
10 mM	0.2767 mL	1.3834 mL	2.7669 mL	13.8343 mL

DMF

	1mg	5mg	10mg	50mg
20 mM	0.1383 mL	0.6917 mL	1.3834 mL	6.9172 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Citations

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc