Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty

PDGF-BB Protein, Human, Recombinant

(Synonyms: PDGF-BB, PDGFBB) Copy Product Info

Synonyms: PDGF-BB, PDGFBB

Catalog No. TMPJ-00735 Copy Product Info
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
PDGF-BB Protein, Human, Recombinant
Pack SizePriceUSA StockGlobal StockQuantity
10 μg$1187-10 days7-10 days
50 μg$3507-10 days7-10 days
500 μg$1,6307-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Questions
TargetMol
View More

Batch Information

Select Batch
Purity:SDS-PAGE: 98.3%; SEC-HPLC: >99.9%
Appearance:Lyophilized powder
Color:White
Contact us for more batch information

Product Introduction

Bioactivity
Description
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
Species
Human
Expression System
E. coli
TagTag Free
Accession NumberP01127
Amino AcidSer82-Thr190
ConstructionSer82-Thr190
Protein Purity
Greater than 98% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC.
https://cdn.targetmol.com/group3/M00/13/6F/CgoaEWZG002EWvmxAAAAAKdYRtE751.png,https://cdn.targetmol.com/group3/M00/13/6F/CgoaEWZG002EYk-rAAAAAIB7OEs359.png
Endotoxin< 0.02 ng/µg (0.2 EU/µg) as determined by LAL test.
FormulationLyophilized from a 0.2 μm filtered solution of 20 mM NaAC-HAC,4% Mannitol, pH 4.5.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsPDGF-BB, PDGFBB
Research Background
Chemical Properties
Molecular Weight14 KDa (reducing condition)
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: PDGF-BB Protein, Human, Recombinant chemical structure | PDGF-BB Protein, Human, Recombinant molecular weight