LRP10 (low-density lipoprotein Receptor Related Protein 10) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes a low-density lipoprotein receptor family protein. A similar protein in mouse is thought to play a role in the uptake of apolipoprotein E-containing lipoproteins. Human LRP10 cDNA encodes a 1905 amino acid type I membrane protein consisting of five functional domains characteristic of the LDLR gene family. It is widely expressed in the esophagus, colon, and other tissues. LRP10 plays a significant role in brain physiology other than lipoprotein metabolism. It is associated with a series of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease which share genetic risk factors and pathophysiological processes with amyotrophic lateral sclerosis (ALS).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 5 days | $ 700.00 |
Description | LRP10 (low-density lipoprotein Receptor Related Protein 10) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes a low-density lipoprotein receptor family protein. A similar protein in mouse is thought to play a role in the uptake of apolipoprotein E-containing lipoproteins. Human LRP10 cDNA encodes a 1905 amino acid type I membrane protein consisting of five functional domains characteristic of the LDLR gene family. It is widely expressed in the esophagus, colon, and other tissues. LRP10 plays a significant role in brain physiology other than lipoprotein metabolism. It is associated with a series of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease which share genetic risk factors and pathophysiological processes with amyotrophic lateral sclerosis (ALS). |
Species | Human |
Expression System | HEK293 |
Tag | His |
Accession Number | Q7Z4F1-1 |
Synonyms | MST087, LRP9, low density lipoprotein receptor-related protein 10, MSTP087 |
Construction | A DNA sequence encoding the human LRP10 (Q7Z4F1-1) extracellular domain (Met 1-Lys 440) was fused with a polyhistidine tag at the C-terminus. |
Protein Purity | > 97 % as determined by SDS-PAGE |
Molecular Weight | 47.5kDa (predicted) |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
Formulation | Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA. |
Reconstitution | A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information. |
Stability & Storage |
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | LRP10 (low-density lipoprotein Receptor Related Protein 10) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes a low-density lipoprotein receptor family protein. A similar protein in mouse is thought to play a role in the uptake of apolipoprotein E-containing lipoproteins. Human LRP10 cDNA encodes a 1905 amino acid type I membrane protein consisting of five functional domains characteristic of the LDLR gene family. It is widely expressed in the esophagus, colon, and other tissues. LRP10 plays a significant role in brain physiology other than lipoprotein metabolism. It is associated with a series of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease which share genetic risk factors and pathophysiological processes with amyotrophic lateral sclerosis (ALS). |
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Please read the User Guide of Recombinant Proteins for more specific information.
LRP-10 Protein, Human, Recombinant (His) MST087 LRP 9 MST-087 LRP-9 MST 087 MSTP 087 MSTP-087 LRP9 low density lipoprotein receptor-related protein 10 MSTP087 recombinant recombinant-proteins proteins protein