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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Hydroxy-PEG24-CH2-Boc is a PEG-based linker utilized in PROTACs, facilitating the connection of two essential ligands critical for PROTAC molecule formation, thereby enabling selective protein degradation through the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands connected by a linker; one ligand binds to an E3 ubiquitin ligase and the other targets the specific protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Alias | HO-PEG24-CH2COOtBu |
Molecular Weight | 1189.42 |
Formula | C54H108O27 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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