Killer cell lectin-like receptor subfamily F member 1 (KLRF1) is known as NKp80. Human NKp80, a member of the C-type lectin family of proteins (1 - 3), is 231 aa in length with a 38 amino acid (aa) cytoplasmic region, a 21 aa transmembrane region, and a 172 aa extracellular domain (ECD). The protein strongly expressed in peripheral blood leukocytes and spleen, with weaker expression in lymph node and adult liver, and no expression detected in bone marrow, thymus, and fetal liver. Its' function involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 μg | 5 days | $ 107.00 | |
50 μg | 5 days | $ 324.00 | |
500 μg | 5 days | $ 1,950.00 | |
1 mg | 5 days | $ 2,940.00 |
Description | Killer cell lectin-like receptor subfamily F member 1 (KLRF1) is known as NKp80. Human NKp80, a member of the C-type lectin family of proteins (1 - 3), is 231 aa in length with a 38 amino acid (aa) cytoplasmic region, a 21 aa transmembrane region, and a 172 aa extracellular domain (ECD). The protein strongly expressed in peripheral blood leukocytes and spleen, with weaker expression in lymph node and adult liver, and no expression detected in bone marrow, thymus, and fetal liver. Its' function involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts. |
Species | Human |
Expression System | Human Cells |
Tag | N-6His |
Accession Number | Q9NZS2 |
Synonyms | Lectin-like receptor F1, C-type lectin domain family 5 member C, KLRF1, Activating coreceptor NKp80, CLEC5C, Killer cell lectin-like receptor subfamily F member 1 |
Amino Acid | Val66-Tyr231 |
Construction | Recombinant Killer cell lectin-like receptor subfamily F member 1 is produced by our Mammalian expression system and the target gene encoding Val66-Tyr231 is expressed with a 6His tag at the N-terminus. |
Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
Molecular Weight | 25-35 KDa, reducing conditions |
Endotoxin | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Stability & Storage |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
Shipping |
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Research Background | Killer cell lectin-like receptor subfamily F member 1 (KLRF1) is known as NKp80. Human NKp80, a member of the C-type lectin family of proteins (1 - 3), is 231 aa in length with a 38 amino acid (aa) cytoplasmic region, a 21 aa transmembrane region, and a 172 aa extracellular domain (ECD). The protein strongly expressed in peripheral blood leukocytes and spleen, with weaker expression in lymph node and adult liver, and no expression detected in bone marrow, thymus, and fetal liver. Its' function involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts. |
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Please read the User Guide of Recombinant Proteins for more specific information.
NKp80/KLRF1 Protein, Human, Recombinant (His) KLRF 1 Lectin-like receptor F1 C-type lectin domain family 5 member C KLRF1 Activating coreceptor NKp80 CLEC5C KLRF-1 Killer cell lectin-like receptor subfamily F member 1 recombinant recombinant-proteins proteins protein