IL-1RL2 Protein, Human, Recombinant (hFc)

Name: IL-1RL2 Protein, Human, Recombinant (hFc)
Brand: TargetMol
SKU: TMPY-00364
Price: 48 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: interleukin 1 receptor like 2, IL-36R, IL1R-rp2, IL-1Rrp2, IL1RRP2) Copy Product Info

Synonyms: interleukin 1 receptor like 2, IL-36R, IL1R-rp2, IL-1Rrp2, IL1RRP2

Catalog No. TMPY-00364 Copy Product Info

IL-1RL2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.6 kDa and the accession number is Q9HB29-1.

Pack Size	Price	USA Stock	Global Stock
5 µg	$48	-	In Stock
10 µg	$79	-	In Stock
20 µg	$129	7-10 days	7-10 days
50 µg	$250	7-10 days	7-10 days
100 µg	$483	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Human IL-1 Rrp-2, hFc Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-IL-1 Rrp-2 Antibody, hFc Tag with the EC50 of 20.9 ng/ml determined by ELISA (QC Test).Human IL-1 Rrp-2, hFc Tag captured on CM5 Chip via Protein A can bind Human IL-1F10, His Tag with an affinity constant of 35.38 μM as determined in SPR assay (Biacore T200).
Description	IL-1RL2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.6 kDa and the accession number is Q9HB29-1.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	Q9HB29-1
Construction	Asp20-Arg335
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	interleukin 1 receptor like 2, IL-36R, IL1R-rp2, IL-1Rrp2, IL1RRP2
Research Background	The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). IL1RL2 is a receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways.

Chemical Properties

Molecular Weight

62.6 kDa (Predicted); 75-110 kDa (Due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.