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CRMP1 Protein, Human, Recombinant

Catalog No. TMPH-01226
Synonyms: ULIP3, Collapsin response mediator protein 1, CRMP1, Dihydropyrimidinase-related protein 1, CRMP-1, Inactive dihydropyrimidinase, ULIP-3, DPYSL1, DRP-1, Unc-33-like phosphoprotein 3

Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance. During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F-actin which results in the rearrangement of the actin cytoskeleton and the collapse of the growth cone. Involved in invasive growth and cell migration. May participate in cytokinesis.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
CRMP1 Protein, Human, Recombinant
Pack Size Availability Price/USD Quantity
20 μg 20 days $ 362.00
100 μg 20 days $ 544.00
1 mg 20 days $ 1,840.00
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Biological Description
Technical Params
Product Properties
Description Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance. During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F-actin which results in the rearrangement of the actin cytoskeleton and the collapse of the growth cone. Involved in invasive growth and cell migration. May participate in cytokinesis.
Species Human
Expression System E. coli
Tag Tag-Free
Accession Number Q14194
Synonyms ULIP3, Collapsin response mediator protein 1, CRMP1, Dihydropyrimidinase-related protein 1, CRMP-1, Inactive dihydropyrimidinase, ULIP-3, DPYSL1, DRP-1, Unc-33-like phosphoprotein 3
Amino Acid MSYQGKKSIPHITSDRLLIKGGRIINDDQSLYADVYLEDGLIKQIGENLIVPGGVKTIEANGRMVIPGGIDVNTYLQKPSQGMTAADDFFQGTRAALVGGTTMIIDHVVPEPGSSLLTSFEKWHEAADTKSCCDYSLHVDITSWYDGVREELEVLVQDKGVNSFQVYMAYKDVYQMSDSQLYEAFTFLKGLGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAITIAGRINCPVYITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLTSLLACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEERMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKLKTITAKSHKSAVEYNIFEGMECHGSPLVVISQGKIVFEDGNINVNKGMGRFIPRKAFPEHLYQRVKIRNKVFGLQGVSRGMYDGPVYEVPATPKYATPAPSAKSSPSKHQPPPIRNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGRSNITSLG Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
Construction 1-572 aa
Protein Purity > 90% as determined by SDS-PAGE.
Molecular Weight 62.2 kDa (predicted)
Formulation Tris-based buffer,50% glycerol
Reconstitution A hardcopy of COA with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Research Background Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance. During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F-actin which results in the rearrangement of the actin cytoskeleton and the collapse of the growth cone. Involved in invasive growth and cell migration. May participate in cytokinesis.

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Keywords

CRMP1 Protein, Human, Recombinant ULIP3 Collapsin response mediator protein 1 CRMP1 Dihydropyrimidinase-related protein 1 CRMP-1 Inactive dihydropyrimidinase ULIP-3 DPYSL1 DRP-1 Unc-33-like phosphoprotein 3 recombinant recombinant-proteins proteins protein

 

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