Shopping Cart

Your shopping cart is currently empty

Pinobanksin

Name: Pinobanksin
Brand: TargetMol
SKU: TN2076
Price: 70 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. TN2076Cas No. 548-82-3

Alias 3,5,7-Trihydroxyflavanon

Pinobanksin is a natural flavonoid that induces apoptosis in B-cell lymphoma cell lines and SH-SY5Y cells. It is a potent antioxidant that inhibits the peroxidation of low-density lipoprotein (LDL) and is able to occupy the catalytic center of xanthine oxidase (XO) and thus inhibit it. Pinobanksin also exhibits antimicrobial, anti-inflammatory, antiparasitic, anti-mutagenic, anti-proliferative, and anti-angiogenic effects.

Pinobanksin

🥰Excellent

Purity: 99.92%

Catalog No. TN2076Alias 3,5,7-TrihydroxyflavanonCas No. 548-82-3

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$70	-	In Stock
5 mg	$168	-	In Stock
10 mg	$248	-	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.92%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Pinobanksin is a natural flavonoid that induces apoptosis in B-cell lymphoma cell lines and SH-SY5Y cells. It is a potent antioxidant that inhibits the peroxidation of low-density lipoprotein (LDL) and is able to occupy the catalytic center of xanthine oxidase (XO) and thus inhibit it. Pinobanksin also exhibits antimicrobial, anti-inflammatory, antiparasitic, anti-mutagenic, anti-proliferative, and anti-angiogenic effects.
In vitro	Methods: PC12 cells were treated with Pinobanksin (0.1-1 mg/mL, 24 hours), and cell viability and ROS content were measured by MTT assay. Results: The survival rate of PC12 cells exceeded 85%, and Pinobanksin showed no significant toxicity. It could also reduce the intracellular ROS level by 31.82% at a concentration of 1 mg/mL, demonstrating the intracellular antioxidant effect of Pinobanksin. [2]
Synonyms	3,5,7-Trihydroxyflavanon

Chemical Properties

Molecular Weight	272.25
Formula	C₁₅H₁₂O₅
Cas No.	548-82-3
Smiles	O=C1C=2C(O[C@@H]([C@H]1O)C3=CC=CC=C3)=CC(O)=CC2O
Relative Density.	1.497g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (293.85 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (12.12 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6731 mL	18.3655 mL	36.7309 mL	183.6547 mL
5 mM	0.7346 mL	3.6731 mL	7.3462 mL	36.7309 mL
10 mM	0.3673 mL	1.8365 mL	3.6731 mL	18.3655 mL
20 mM	0.1837 mL	0.9183 mL	1.8365 mL	9.1827 mL
50 mM	0.0735 mL	0.3673 mL	0.7346 mL	3.6731 mL
100 mM	0.0367 mL	0.1837 mL	0.3673 mL	1.8365 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc