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Anti-Complement C3 Antibody (3G106)

(Synonyms: Complement Component C3a, C3a, Anaphylatoxin) Copy Product Info
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Synonyms: Complement Component C3a, C3a, Anaphylatoxin

Catalog No. TMAH-00128 Copy Product Info
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Anti-Complement C3 Antibody (3G106) is an antibody targeting Complement C3. Anti-Complement C3 Antibody (3G106) can be used in ELISA,IHC.
Anti-Complement C3 Antibody
(3G106)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2097-10 days7-10 days
100 μL$3477-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Complement C3 Antibody (3G106) is an antibody targeting Complement C3. Anti-Complement C3 Antibody (3G106) can be used in ELISA,IHC.
SynonymsComplement Component C3a, C3a, Anaphylatoxin
Ig Type
Rabbit IgG
Clone
3G106
Reactivity
Human
Application
Recommended Dose
IHC:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationSecreted.
Tissue SpecificityPlasma. The acylation stimulating protein (ASP) is expressed in adipocytes and released into the plasma during both the fasting and postprandial periods.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundC3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. Acts as a chemoattractant for neutrophils in chronic inflammation. adipogenic hormone that stimulates triglyceride (TG) synthesis and glucose transport in adipocytes, regulating fat storage and playing a role in postprandial TG clearance. Appears to stimulate TG synthesis via activation of the PLC, MAPK and AKT signaling pathways. Ligand for C5AR2. Promotes the phosphorylation, ARRB2-mediated internalization and recycling of C5AR2.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human C3 / C3a
Antigen Species
Human
Gene Name
C3
Gene ID
Uniprot ID
Biology Area
Neuroscience, Immunology
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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