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Anti-Complement C3 Antibody (3G106) (Synonyms: Complement Component C3a, C3a, Anaphylatoxin)
Catalog No. TMAH-00128 Copy Product Info
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Anti-Complement C3 Antibody (3G106) is an antibody targeting Complement C3. Anti-Complement C3 Antibody (3G106) can be used in ELISA,IHC.
Anti-Complement C3 Antibody (3G106)
Copy Product Info🥰Excellent
Catalog No. TMAH-00128
Synonyms Complement Component C3a, C3a, Anaphylatoxin
Anti-Complement C3 Antibody (3G106) is an antibody targeting Complement C3. Anti-Complement C3 Antibody (3G106) can be used in ELISA,IHC.
Anti-Complement C3 Antibody
(3G106)
(3G106)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $347 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Complement C3 Antibody (3G106) is an antibody targeting Complement C3. Anti-Complement C3 Antibody (3G106) can be used in ELISA,IHC. |
| Synonyms | Complement Component C3a, C3a, Anaphylatoxin |
| Ig Type | Rabbit IgG |
| Clone | 3G106 |
| Reactivity | Human |
| Verified Activity | IHC image of TMAH-00128 diluted at 1:100 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| Application | |
| Recommended Dose | IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Secreted. |
| Tissue Specificity | Plasma. The acylation stimulating protein (ASP) is expressed in adipocytes and released into the plasma during both the fasting and postprandial periods. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. Acts as a chemoattractant for neutrophils in chronic inflammation. adipogenic hormone that stimulates triglyceride (TG) synthesis and glucose transport in adipocytes, regulating fat storage and playing a role in postprandial TG clearance. Appears to stimulate TG synthesis via activation of the PLC, MAPK and AKT signaling pathways. Ligand for C5AR2. Promotes the phosphorylation, ARRB2-mediated internalization and recycling of C5AR2. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human C3 / C3a |
| Antigen Species | Human |
| Gene Name | C3 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Neuroscience, Immunology |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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