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Anti-Complement factor H/CFH Antibody (2Z553) (Synonyms: Sas-1, Sas1, NOM, Mud-1, complement factor H)
Catalog No. TMAY-01107 Copy Product Info
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Anti-Complement factor H/CFH Antibody (2Z553) is a Rabbit antibody targeting Complement factor H/CFH. Anti-Complement factor H/CFH Antibody (2Z553) can be used in ELISA.
Anti-Complement factor H/CFH Antibody (2Z553)
Copy Product Info🥰Excellent
Catalog No. TMAY-01107
Synonyms Sas-1, Sas1, NOM, Mud-1, complement factor H
Anti-Complement factor H/CFH Antibody (2Z553) is a Rabbit antibody targeting Complement factor H/CFH. Anti-Complement factor H/CFH Antibody (2Z553) can be used in ELISA.
Anti-Complement factor H/CFH Antibody
(2Z553)
(2Z553)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $270 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Complement factor H/CFH Antibody (2Z553) is a Rabbit antibody targeting Complement factor H/CFH. Anti-Complement factor H/CFH Antibody (2Z553) can be used in ELISA. |
| Synonyms | Sas-1, Sas1, NOM, Mud-1, complement factor H |
| Ig Type | Rabbit IgG |
| Clone | 2Z553 |
| Reactivity | Human |
| Specificity | Human Factor H |
| Application | |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Complement Factor H / CFH (rh Complement Factor H / CFH; TMPY-01439; NP_000177.2; Ser 860-Arg 1231). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Complement factor H, also known as H factor 1, and CFH, is a sialic acid containing glycoprotein that plays an integral role in the regulation of the complement-mediated immune system that is involved in microbial defense, immune complex processing, and programmed cell death. Factor H protects host cells from injury resulting from unrestrained complement activation. CFH regulates complement activation on self cells by possessing both cofactor activity for the Factor I mediated C3b cleavage, and decay accelerating activity against the alternative pathway C3 convertase, C3bBb. CFH protects self cells from complement activation but not bacteria/viruses. Due to the central role that CFH plays in the regulation of complement, there are many clinical implications arrising from aberrant CFH activity. Mutations in the Factor H gene are associated with severe and diverse diseases including the rare renal disorders hemolytic uremic syndrome (HUS) and membranoproliferative glomerulonephritis (MPGN) also termed dense deposit disease (DDD), membranoproliferative glomuleronephritis type II or dense deposit disease, as well as the more frequent retinal disease age related macular degeneration (AMD). In addition to its complement regulatory activities, factor H has multiple physiological activities and 1) acts as an extracellular matrix component, 2) binds to cellular receptors of the integrin type, and 3) interacts with a wide selection of ligands, such as the C-reactive protein, thrombospondin, bone sialoprotein, osteopontin, and heparin. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human Complement Factor H / CFH protein (TMPY-01439) |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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