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TSTA3 Protein, Human, Recombinant (His)

Catalog No. TMPJ-01111
Synonyms: GDP-L-Fucose Synthase, Short-Chain Dehydrogenase/Reductase Family 4E Member 1, Red Cell NADP(H)-Binding Protein, TSTA3, GDP-4-Keto-6-Deoxy-D-Mannose-3, Protein FX, 5-Epimerase-4-Reductase, SDR4E1

GDP-L-Fucose Synthase is a NADP(H)-binding protein. It catalyzes the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-dexoymannose to GDP-L-fucose. GDP-L-Fucose is the substrate of several fucosyltransferase, involving the expression of mamy glycoconjugates, including blood group ABH antigens and development adhesion antigens. Mutations in the TSTA3 gene may cause leukocyte adhesion deficiency type II.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
TSTA3 Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 184.00
50 μg 5 days $ 545.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description GDP-L-Fucose Synthase is a NADP(H)-binding protein. It catalyzes the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-dexoymannose to GDP-L-fucose. GDP-L-Fucose is the substrate of several fucosyltransferase, involving the expression of mamy glycoconjugates, including blood group ABH antigens and development adhesion antigens. Mutations in the TSTA3 gene may cause leukocyte adhesion deficiency type II.
Species Human
Expression System E. coli
Tag C-6His
Accession Number Q13630
Synonyms GDP-L-Fucose Synthase, Short-Chain Dehydrogenase/Reductase Family 4E Member 1, Red Cell NADP(H)-Binding Protein, TSTA3, GDP-4-Keto-6-Deoxy-D-Mannose-3, Protein FX, 5-Epimerase-4-Reductase, SDR4E1
Amino Acid Met1-Lys321
Construction Recombinant Human GDP-L-Fucose Synthase is produced by our E.coli expression system and the target gene encoding Met1-Lys321 is expressed with a 6His tag at the C-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 40 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Stability & Storage

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Shipping

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
Research Background GDP-L-Fucose Synthase is a NADP(H)-binding protein. It catalyzes the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-dexoymannose to GDP-L-fucose. GDP-L-Fucose is the substrate of several fucosyltransferase, involving the expression of mamy glycoconjugates, including blood group ABH antigens and development adhesion antigens. Mutations in the TSTA3 gene may cause leukocyte adhesion deficiency type II.

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Keywords

TSTA3 Protein, Human, Recombinant (His) TSTA 3 GDP-L-Fucose Synthase TSTA-3 Short-Chain Dehydrogenase/Reductase Family 4E Member 1 Red Cell NADP(H)-Binding Protein TSTA3 GDP-4-Keto-6-Deoxy-D-Mannose-3 Protein FX 5-Epimerase-4-Reductase SDR4E1 recombinant recombinant-proteins proteins protein

 

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