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Anti-Phospho-PDGFRB (Y740) Antibody (1I961)

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Catalog No. TMAC-03115

Anti-Phospho-PDGFRB (Y740) Antibody (1I961) is a Rabbit antibody targeting Phospho-PDGFRB (Y740). Anti-Phospho-PDGFRB (Y740) Antibody (1I961) can be used in WB,ICC/IF.

Anti-Phospho-PDGFRB (Y740) Antibody (1I961)

Anti-Phospho-PDGFRB (Y740) Antibody (1I961)

😃Good
Catalog No. TMAC-03115
Anti-Phospho-PDGFRB (Y740) Antibody (1I961) is a Rabbit antibody targeting Phospho-PDGFRB (Y740). Anti-Phospho-PDGFRB (Y740) Antibody (1I961) can be used in WB,ICC/IF.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4967-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-PDGFRB (Y740) Antibody (1I961) is a Rabbit antibody targeting Phospho-PDGFRB (Y740). Anti-Phospho-PDGFRB (Y740) Antibody (1I961) can be used in WB,ICC/IF.
Ig Type
IgG
Reactivity
Mouse,Rat
Application
Recommended Dose
WB: 1:1000; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionHybridoma Monoclonal Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundPlatelet Derived Growth Factor (PDGF) is a mitogen for mesenchyme- and glia-derived cells. PDGF consists of two chains, A and B, which dimerize to form functionally distinct isoforms, PDGF-AA, PDGF-AB, and PDGF-BB. These three isoforms bind with different affinities to two receptor types, a and b, which are endowed with protein tyrosine kinase domains and undergo either homo- or heterodimerization as a consequence of ligand binding. Ligand stimulation of PDGFR-b leads to autophosphorylation at Tyr-857, which is the major autophosphorylation site, and Tyr-751, which is the major in vitro phosphorylation site. Autophosphorylation of Tyr-751, which lies in the kinase insert region, is required for binding of phosphatidylinositol-3 kinase to the receptor. These auto-phosphorylation events largely contribute to signal transduction through the PDGF receptor.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A synthesized phosphopeptide: human PDGF Receptor beta around the phosphorylation site of Tyr740
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 190 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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