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Paroxetine

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Catalog No. T8708Cas No. 61869-08-7

Paroxetine is a inhibitor of serotonin uptake that is effective in the treatment of depression.

Paroxetine
Other Forms of Paroxetine:

Paroxetine

😃Good
Purity: 99.45%
Catalog No. T8708Cas No. 61869-08-7
Paroxetine is a inhibitor of serotonin uptake that is effective in the treatment of depression.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$30In Stock-
50 mg$41In Stock-
100 mg$55In Stock-
500 mg$162BackorderBackorder
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.45%
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COA HPLC HNMR

Product Introduction

Bioactivity
Description
Paroxetine is a inhibitor of serotonin uptake that is effective in the treatment of depression.
Chemical Properties
Molecular Weight329.37
FormulaC19H20FNO3
Cas No.61869-08-7
SmilesC(OC=1C=C2C(=CC1)OCO2)[C@H]3[C@@H](CCNC3)C4=CC=C(F)C=C4
Relative Density.1.1844 g/cm3 (Estimated)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 60 mg/mL (182.17 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.07 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0361 mL15.1805 mL30.3610 mL151.8050 mL
5 mM0.6072 mL3.0361 mL6.0722 mL30.3610 mL
10 mM0.3036 mL1.5180 mL3.0361 mL15.1805 mL
20 mM0.1518 mL0.7590 mL1.5180 mL7.5902 mL
50 mM0.0607 mL0.3036 mL0.6072 mL3.0361 mL
100 mM0.0304 mL0.1518 mL0.3036 mL1.5180 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

SLC6A4SERTSerotoninTransporterSerotonin Transporterserotonin reuptakeserotoninParoxetinenorepinephrineInhibitorinhibitBeta ReceptorAdrenergic Receptor5-HTT
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