Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Thalidomide-Piperazine-PEG2-NH2 is a synthetic E3 ligase ligand-linker conjugate that combines the cereblon ligand derived from Thalidomide with a linker commonly utilized in PROTAC technology.
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Description | Thalidomide-Piperazine-PEG2-NH2 is a synthetic E3 ligase ligand-linker conjugate that combines the cereblon ligand derived from Thalidomide with a linker commonly utilized in PROTAC technology. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
Synonyms | Thalidomide-Piperazine-PEG2-NH2 |
Molecular Weight | 473.53 |
Formula | C23H31N5O6 |
CAS No. | 2357110-14-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Thalidomide-Piperazine-PEG2-NH2 2357110-14-4 Thalidomide Piperazine PEG2 NH2 Thalidomide-Piperazine-PEG-2-NH2 ThalidomidePiperazinePEG2NH2 inhibitor inhibit