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Anti-FOLR2 Antibody (6I902)
😃Good
Catalog No. TMAY-01765
Alias β-HFR, FR-β, FR-P3, FR-BETA, folate receptor 2 (fetal), FBP/PL-1, FBP, BETA-HFR
Anti-FOLR2 Antibody (6I902) is a Rabbit antibody targeting FOLR2. Anti-FOLR2 Antibody (6I902) can be used in IHC-P.
Anti-FOLR2 Antibody (6I902)
Anti-FOLR2 Antibody (6I902)
😃Good
Catalog No. TMAY-01765Alias β-HFR, FR-β, FR-P3, FR-BETA, folate receptor 2 (fetal), FBP/PL-1, FBP, BETA-HFR
Anti-FOLR2 Antibody (6I902) is a Rabbit antibody targeting FOLR2. Anti-FOLR2 Antibody (6I902) can be used in IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-FOLR2 Antibody (6I902) is a Rabbit antibody targeting FOLR2. Anti-FOLR2 Antibody (6I902) can be used in IHC-P. |
| Alias | β-HFR, FR-β, FR-P3, FR-BETA, folate receptor 2 (fetal), FBP/PL-1, FBP, BETA-HFR |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 6I902 |
| Reactivity | Human |
| Verified Activity | 1. Immunochemical staining of human FOLR2 in human spleen with rabbit monoclonal antibody at 1:5000 dilution,formalin-fixed paraffin embedded sections. 2. Immunochemical staining of human FOLR2 in human placenta with rabbit monoclonal antibody at 1:5000 dilution,formalin-fixed paraffin embedded sections. |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:2000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human FOLR2 (rh FOLR2; TMPY-01280; P14207-1; Met1-His228). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Folate receptor beta, also known as Folate receptor 2, FBP, and FOLR2, is a member of the folate receptor family. FOLR2 is expressed in placenta and hematopoietic cells. The expression of FOLR2 is increased in malignant tissues. Members of the Folate receptor family members (FOLRs) have a high affinity for folic acid and for several reduced folic acid derivatives. They mediate the delivery of 5-methyltetrahydrofolate to the interior of, out of within, or between cells in a process known as potocytosis. FOLR2 has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. The FOLR2 protein was originally thought to exist only in placenta, but is also detected in spleen, bone marrow, and thymus. FOLR2 is a marker for macrophages generated in the presence of M-CSF, but not GM-CSF. Its expression correlates with increased folate uptake ability. Folate conjugates of therapeutic drugs are a potential immunotherapy tool to target tumor-associated macrophages. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human FOLR2 protein (TMPY-01280) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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