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Anti-IL12RB1 Polyclonal Antibody is a Rabbit antibody targeting IL12RB1. Anti-IL12RB1 Polyclonal Antibody can be used in FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $221 | 7-10 days | |
100 μL | $373 | 7-10 days | |
200 μL | $528 | 7-10 days |
Description | Anti-IL12RB1 Polyclonal Antibody is a Rabbit antibody targeting IL12RB1. Anti-IL12RB1 Polyclonal Antibody can be used in FCM. |
Alias | interleukin-12 receptor β-1 chain, interleukin-12 receptor subunit β-1, interleukin-12 receptor subunit beta-1, interleukin-12 receptor beta-1 chain, IL-12R-β-1, IL-12R-β1, IL-12R-beta-1, IL-12R-BETA1, IL-12RB1, IL12RB1, IL12RB, IL-12R subunit β-1, IL-12R subunit beta-1, IL12R, IL-12 receptor β component, IL-12 receptor subunit β-1, IL-12 receptor subunit beta-1, IL-12 receptor beta component, CD212 antigen, CD212 |
Ig Type | IgG |
Reactivity | Mouse (predicted:Rat) |
Verified Activity | Blank control: RAW264.7. Primary Antibody (green line): Rabbit Anti-IL12RB1 antibody (TMAB-00942) Dilution: 1 μg/Test; Secondary Antibody (white blue line): Goat anti-rabbit IgG-AF488 Dilution: 0.5 μg/Test. Isotype control (orange line): Normal Rabbit IgG Protocol The cells were incubated in 5% BSA to block non-specific protein-protein interactions for 30 min at room temperature. Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. |
Application | |
Recommended Dose | FCM: 1ug/Test |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Membrane; Single-pass type I membrane protein. |
Construction | Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Research Background | The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The lack of expression of this gene was found to result in the immunodeficiency of patients with severe mycobacterial and Salmonella infections. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq]. |
Immunogen | KLH conjugated synthetic peptide: mouse IL-12RB1 |
Antigen Species | Mouse |
Gene ID | |
Uniprot ID | |
Biology Area | Interleukins |
Molecular Weight | Theoretical: 80 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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