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IL-1 Rrp2/IL-1 R6 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 37.1 kDa and the accession number is G8F338.

| Pack Size | Price | Availability | Quantity | 
|---|---|---|---|
| 5 μg | $51 | 7-10 days | |
| 10 μg | $80 | 7-10 days | |
| 20 μg | $129 | 7-10 days | |
| 50 μg | $248 | 7-10 days | |
| 100 μg | $418 | 7-10 days | |
| 200 μg | $757 | 7-10 days | |
| 500 μg | $1,670 | 7-10 days | 
| Biological Activity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.  | 
| Description | IL-1 Rrp2/IL-1 R6 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 37.1 kDa and the accession number is G8F338.  | 
| Species | Cynomolgus  | 
| Expression System | HEK293 Cells  | 
| Tag | C-His | 
| Accession Number | G8F338 | 
| Synonyms | IL-36R,IL1RRP2,IL1RL2,IL-1 Rrp2,IL-1 R6  | 
| Construction | Asp20-Arg335  | 
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC  | 
| Molecular Weight | 37.1 kDa (predicted). Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result. | 
| Endotoxin | < 1 EU/μg by the LAL method. | 
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. | 
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.  | 
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.  | 
| Shipping | In general, Lyophilized powders are shipping with blue ice. | 
| Research Background | The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). IL1RL2 is a receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways.  | 

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