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Anti-Plectin Antibody (4J312)

(Synonyms: PLTN, Plectin-1, Plectin 6, Plectin 1 intermediate filament binding protein 500kDa, Plectin 1, Plectin, PLEC1b, PLEC1, PLEC_HUMAN, pleC, PCN, Hemidesmosomal protein 1, HD1, EBSO, EBS1) Copy Product Info
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Synonyms: PLTN, Plectin-1, Plectin 6, Plectin 1 intermediate filament binding protein 500kDa, Plectin 1, Plectin, PLEC1b, PLEC1, PLEC_HUMAN, pleC, PCN, Hemidesmosomal protein 1, HD1, EBSO, EBS1

Catalog No. TMAC-03379 Copy Product Info
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Anti-Plectin Antibody (4J312) is a Rabbit antibody targeting Plectin. Anti-Plectin Antibody (4J312) can be used in IHC,IP,WB.
Anti-Plectin Antibody
(4J312)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Plectin Antibody (4J312) is a Rabbit antibody targeting Plectin. Anti-Plectin Antibody (4J312) can be used in IHC,IP,WB.
SynonymsPLTN, Plectin-1, Plectin 6, Plectin 1 intermediate filament binding protein 500kDa, Plectin 1, Plectin, PLEC1b, PLEC1, PLEC_HUMAN, pleC, PCN, Hemidesmosomal protein 1, HD1, EBSO, EBS1
Ig Type
IgG
Clone
4J312
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000; IHC: 1:100-500
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundPlectin is an abundant cytoskeletal protein that is involved in cytoplasm stabilization. Plectin has been shown to crosslink intermediate filaments to microtubules and microfilaments, and to anchor intermediate filaments to the plasma and nuclear membranes. Plectin binds both Lamin B and vimentin, and this binding is regulated by a variety of protein kinases. Phosphorylation by PKA or PKC results in decreased binding to Lamin B, and phosphorylation by PKA enhances the plectin-vimentin interactions. Plectin is also a substrate for p34cdc2 kinase. Several alternative splice isoforms of plectin are known to exist. Mutations in human plectin are known to cause epidermolysis bullosa simplex with muscular dystrophy (EBS-MD).
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 531 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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