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CD63 Protein, Human, Recombinant (His)

Catalog No. TMPY-02099
Synonyms: OMA81H, TSPAN30, LAMP-3, MLA1, ME491, CD63 molecule

CD63 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13 kDa and the accession number is P08962-1.

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CD63 Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
100 μg In stock $ 386.00
200 μg 5 days $ 682.00
500 μg 5 days $ 1,440.00
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Biological Description
Technical Params
Product Properties
References and Literature
Biological Information Testing in progress
Description CD63 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13 kDa and the accession number is P08962-1.
Species Human
Expression System HEK293 Cells
Tag C-His
Accession Number P08962-1
Synonyms OMA81H, TSPAN30, LAMP-3, MLA1, ME491, CD63 molecule
Construction The second extracellular domain of Human CD63 (P08962-1) (Ala 103-Val 203) was fused with a polyhistidine tag at the C-terminus and a signal peptide at the N-terminus.
Protein Purity > 95 % as determined by SDS-PAGE

Molecular Weight 13 kDa (predicted)
Endotoxin < 1.0 EU/μg of the protein as determined by the LAL method.
Formulation Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice.

Research Background The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 63 (CD63) is a member of the CD family and the transmembrane 4 superfamily, also known as the tetraspanin family. CD63 is a cell surface glycoprotein characterized by the presence of four hydrophobic domains. CD63 had functions in mediating signal transduction processes and then regulate a variety of cellular processes such as cell proliferation, activation and motility. It has been reported that CD63 protein associated with tumor progression and served as a blood platelet activation marker and the deficiency of this protein may be associated with Hermansky-Pudlak syndrome.

References and Literature

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Keywords

CD63 Protein, Human, Recombinant (His) MLA 1 OMA81H ME 491 LAMP3 TSPAN30 LAMP 3 TSPAN 30 LAMP-3 ME-491 MLA1 TSPAN-30 MLA-1 ME491 CD63 molecule recombinant recombinant-proteins proteins protein

 

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